FAIM3 anticorps (Fas Apoptotic Inhibitory Molecule 3) (AA 80-130) (Biotin)

Details for Product anti-FAIM3 Antibody No. ABIN2690130
Antigène
Épitope
AA 80-130
14
5
5
4
2
1
1
1
1
Reactivité
Humain
43
8
4
Hôte
Lapin
41
7
Clonalité
Polyclonal
Conjugué
Cet anticorp FAIM3 est conjugé à/à la Biotin
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
27
14
13
10
4
2
2
1
1
1
Options
Immunogène KLH conjugated synthetic peptide derived from human FAIM3
Isotype IgG
Purification Purified by Protein A.
Antigène
Autre désignation FAIM3 (FAIM3 Antibody Extrait)
Sujet

May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.

Subcellular location: Extracellular, Secreted, Cell membrane

Synonyms: TOSO, FAIM3, Fas apoptotic inhibitory molecule 3, Regulator of Fas-induced apoptosis Toso

ID gène 9214
UniProt O60667
Indications d'application IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months