IGF1R anticorps (Insulin-Like Growth Factor 1 Receptor) (AA 260-290) (PE)

Details for Product anti-IGF1R Antibody No. ABIN2690172
Antigène
  • CD221
  • IGFIR
  • IGFR
  • JTK13
  • IGFIRC
  • IGFR1
  • IGF-1R
  • IGF1R
  • DKFZp469I0618
  • igf-1r
  • xIGF-1R
  • xIGFR
  • xigf1r
  • A330103N21Rik
  • D930020L01
  • hyft
  • igf-ir
  • IGF-IRa
  • sb:eu1090
  • wu:fi20b10
  • insulin like growth factor 1 receptor
  • insulin-like growth factor 1 receptor
  • insulin-like growth factor I receptor
  • insulin like growth factor 1 receptor S homeolog
  • insulin-like growth factor 1a receptor
  • IGF1R
  • Igf1r
  • igf1r
  • LOC780503
  • LOC100136427
  • igf1r.S
  • igf1ra
Épitope
AA 260-290
50
39
35
33
32
29
23
20
16
15
15
15
15
15
9
9
8
8
7
7
7
6
6
5
5
4
4
4
4
4
4
4
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
532
301
291
20
18
17
12
11
7
4
4
3
2
2
1
Hôte
Lapin
441
94
2
2
1
Clonalité
Polyclonal
Conjugué
Cet anticorp IGF1R est conjugé à/à la PE
23
19
16
15
14
14
14
14
14
13
8
8
8
8
8
7
6
2
Application
Flow Cytometry (FACS)
350
165
150
104
96
73
53
46
20
12
8
7
6
3
3
1
1
Options
Immunogène KLH conjugated synthetic peptide derived from human IGF-1R alpha chain
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others IGF1R products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation IGF1R (IGF1R Antibody Extrait)
Sujet

When present in a hybrid receptor with INSR, binds IGF1. PubMed:12138094 shows that hybrid receptors composed of IGF1R and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin, and that hybrid receptors composed of IGF1R and INSR isoform Short are activated by IGF1, IGF2 and insulin. In contrast, PubMed:16831875 shows that hybrid receptors composed of IGF1R and INSR isoform Long and hybrid receptors composed of IGF1R and INSR isoform Short have similar binding characteristics, both bind IGF1 and have a low affinity for insulin.

Subcellular location: Extracellular

Synonyms: IGFR, CD221, IGFIR, JTK13, Insulin-like growth factor 1 receptor, Insulin-like growth factor I receptor, IGF-I receptor, IGF1R

ID gène 3480
UniProt P08069
Pathways Signalisation RTK, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
Indications d'application FCM 1:20-100
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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