pan Keratin (panKRT) (AA 350-400) anticorps (Alexa Fluor 488)

Détails pour le produit réf. ABIN2690211
Antigène
  • xk70a
  • keratin
  • keratin S homeolog
  • LOC431321
  • krt.S
Épitope
AA 350-400
15
15
14
14
8
6
1
1
Reactivité
Humain, Souris, Rat (Rattus)
317
217
187
108
74
72
57
55
54
51
50
49
27
11
2
2
2
1
1
Hôte
Lapin
205
121
3
Clonalité
Polyclonal
Conjugué
Alexa Fluor 488
12
10
8
8
7
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
5
5
5
4
4
4
4
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
177
175
168
90
84
65
58
24
21
20
14
5
2
2
1
Options
Immunogène KLH conjugated synthetic peptide derived from human CK5
Isotype IgG
Specificité This will target: CK4, CK75, CK3, CK2, CK6C, CK6A, keratin 6E
Purification Purified by Protein A.
Antigène
Autre désignation Keratin
Sujet

Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinising tissue (ie., skin) and non keratinising cells (ie., mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. At least 20 different cytokeratins (CK) in the molecular range of 40 to 70 kDa and isoelectric points of 5 to 8.5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Defects in KRT5 are a cause of epidermolysis bullosa simplex.

Subcellular location: Cytoplasm

Synonyms: CK4, CK75, CK3, CK2, CK6C, CK6A, keratin 6E, P-CK

Indications d'application IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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