GBA3 anticorps (AA 1-150, AA 370-469)

N° du produit ABIN2719165

Détail du produit anti-GBA3 anticorps

Antigène: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Épitope: AA 1-150, AA 370-469

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GBA3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Attributs du produit: Homo sapiens glucosidase, beta, acid 3 (cytosolic) (GBA3), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Human recombinant protein fragment corresponding to amino acids 1-150 and AA 370-469 of human GBA3(NP_066024) produced in E.coli.

Clone: 3E8

Isotype: IgG1

Information d'application

Indications d'application: WB 1:2000, IHC 1:150,

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur GBA3

Antigène: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Autre désignation: GBA3 (GBA3 Produits)

Synonymes: anticorps im:6912508, anticorps CBG, anticorps CBGL1, anticorps GLUC, anticorps KLRP, anticorps glucosylceramidase beta 3, anticorps glucosidase, beta, acid 3 (gene/pseudogene), anticorps glucosidase, beta, acid 3 (cytosolic), anticorps cytosolic beta-glucosidase, anticorps glucosylceramidase beta 3 (gene/pseudogene), anticorps Gba3, anticorps gba3, anticorps GBA3, anticorps LOC100344458

Sujet: GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides (de Graaf et al., 2001 [PubMed 11389701]). GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism (Hayashi et al., 2007 [PubMed 17595169]).

Poids moléculaire: 53.5 kDa

ID gène: 57733

NCBI Accession: NM_020973

HGNC: 57733