PSMB7 anticorps (AA 58-277)

N° du produit ABIN2729942

Détail du produit anti-PSMB7 anticorps

Antigène: PSMB7 (Proteasome (Prosome, Macropain) Subunit, beta Type, 7 (PSMB7))

Épitope: AA 58-277

Reactivité: Humain, Souris, Rat, Singe, Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PSMB7 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Attributs du produit: Homo sapiens proteasome (prosome, macropain) subunit, beta type, 7 (PSMB7)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Human recombinant protein fragment corresponding to amino acids 58-277 of human PSMB7(NP_002790) produced in E.coli.

Clone: 4E3

Isotype: IgG2b

Information d'application

Indications d'application: WB 1:500~2000, IF 1:100,

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur PSMB7

Antigène: PSMB7 (Proteasome (Prosome, Macropain) Subunit, beta Type, 7 (PSMB7))

Autre désignation: PSMB7 (PSMB7 Produits)

Synonymes: anticorps DDBDRAFT_0185624, anticorps DDBDRAFT_0232933, anticorps DDB_0185624, anticorps DDB_0232933, anticorps AU020723, anticorps MC14, anticorps Z, anticorps 20S proteasome subunit beta-7, anticorps proteasome (prosome, macropain) subunit, beta type, 7 S homeolog, anticorps proteasome subunit beta 7, anticorps proteasome (prosome, macropain) subunit, beta type, 7, anticorps proteasome (prosome, macropain) subunit, beta type 7, anticorps psmB7, anticorps psmb7.S, anticorps PSMB7, anticorps Psmb7

Sujet: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit).

Poids moléculaire: 29.8 kDa

ID gène: 5695

NCBI Accession: NM_002799

HGNC: 5695

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA