IKBKG anticorps (AA 40-210)

N° du produit ABIN2745538

Détail du produit anti-IKBKG anticorps

Antigène: IKBKG (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG))

Épitope: AA 40-210

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IKBKG est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Specificité: Recognizes human and mouse IKK-gamma.

Réactivité croisée: Humain, Souris

Purification: Antigen affinity purified.

Immunogène: Recombinant human IKK-gamma (aa 40-210).

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: In TRIS, pH 7.4, containing 50 % glycerol.

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Détails sur IKBKG

Antigène: IKBKG (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG))

Autre désignation: IKKgamma (IKBKG Produits)

Synonymes: anticorps AMCBX1, anticorps FIP-3, anticorps FIP3, anticorps Fip3p, anticorps IKK-gamma, anticorps IP, anticorps IP1, anticorps IP2, anticorps IPD2, anticorps NEMO, anticorps ZC2HC9, anticorps 1110037D23Rik, anticorps AI848108, anticorps AI851264, anticorps AW124339, anticorps IKK[g], anticorps Nemo, anticorps nemo, anticorps fj33c07, anticorps wu:fj33c07, anticorps zgc:113492, anticorps MGC97885, anticorps IKBKG, anticorps IKBKG_1, anticorps IKBKG_2, anticorps CG16910, anticorps DmIKK-gamma, anticorps DmIKKgamma, anticorps Dmel\\CG16910, anticorps Dmikkgamma, anticorps IKK, anticorps IKK[[gamma]], anticorps IKKg, anticorps IKKgamma, anticorps KEY, anticorps Kenny, anticorps Key, anticorps dIKK, anticorps dIKK-gamma, anticorps dmIKKgamma, anticorps inhibitor of nuclear factor kappa B kinase subunit gamma, anticorps inhibitor of kappaB kinase gamma, anticorps inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, anticorps inhibitor of nuclear factor kappa B kinase subunit gamma L homeolog, anticorps kenny, anticorps IKBKG, anticorps Ikbkg, anticorps ikbkg, anticorps ikbkg.L, anticorps IKBKG_1, anticorps key

Sujet: IKK-gamma is the regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappaB, thus leading to the dissociation of the inhibitor/NF-kappaB complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. IKK-gamma is also considered to be a mediator for TAX activation of NF-kappaB and it could be implicated in NF-kappaB-mediated protection from cytokine toxicity. It is essential for viral activation of IRF3 and is involved in TLR3- and IFIH1-mediated antiviral innate response.

UniProt: Q9Y6K9

Pathways: Signalisation NF-kappaB, Signalisation RTK, TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, M Phase, Production of Molecular Mediator of Immune Response, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins