Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

TCR alpha/beta anticorps (FITC)

TCR alpha/beta Reactivité: Rat, Non-Human Primate FACS Hôte: Souris Monoclonal R73 FITC
N° du produit ABIN2749095
  • Antigène Tous les produits TCR alpha/beta
    TCR alpha/beta (T Cell Receptor alpha/beta (TCR alpha/beta))
    Reactivité
    • 21
    • 18
    • 18
    • 7
    • 5
    • 3
    • 3
    • 1
    Rat, Non-Human Primate
    Hôte
    • 46
    • 16
    Souris
    Clonalité
    • 62
    Monoclonal
    Conjugué
    • 17
    • 11
    • 11
    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TCR alpha/beta est conjugé à/à la FITC
    Application
    • 53
    • 30
    • 29
    • 23
    • 19
    • 9
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    The mouse monoclonal R73 recognizes an extracellular epitope TCR alpha/beta, the dominant subtype of T cell receptor expressed in peripheral blood.
    Réactivité croisée (Details)
    Non-Human Primates, Rat
    Purification
    Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogène
    Rat T blasts and erythrocytes
    Clone
    R73
    Isotype
    IgG1 kappa
  • Indications d'application
    Flow cytometry: Recommended dilution: 1-3 μg/mL.
    Commentaires

    The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC.

    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Fuller, Bogdani, Tupling, Jensen, Pefley, Manavi, Cort, Blankenhorn, Mordes, Lernmark, Kwitek: "Genetic dissection reveals diabetes loci proximal to the gimap5 lymphopenia gene." dans: Physiological genomics, Vol. 38, Issue 1, pp. 89-97, (2009) (PubMed).

    Müller, van den Brandt, Odoardi, Tischner, Herath, Flügel, Reichardt: "A CD28 superagonistic antibody elicits 2 functionally distinct waves of T cell activation in rats." dans: The Journal of clinical investigation, Vol. 118, Issue 4, pp. 1405-16, (2008) (PubMed).

    Radojevic, Arsenovic-Ranin, Kosec, Pesic, Pilipovic, Perisic, Plecas-Solarovic, Leposavic: "Neonatal castration affects intrathymic kinetics of T-cell differentiation and the spleen T-cell level." dans: The Journal of endocrinology, Vol. 192, Issue 3, pp. 669-82, (2007) (PubMed).

    Shao, Sun, Kaplan, Sun: "Characterization of rat CD8+ uveitogenic T cells specific for interphotoreceptor retinal-binding protein 1177-1191." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 4, pp. 2849-54, (2004) (PubMed).

    Kerstan, Hünig: "Cutting edge: distinct TCR- and CD28-derived signals regulate CD95L, Bcl-xL, and the survival of primary T cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 3, pp. 1341-5, (2004) (PubMed).

    Li, Thanikachalam, Pang, Kawaharada, Aitouche, Pham: "A clinically relevant CTLA4-Ig-based regimen induces chimerism and tolerance to heart grafts." dans: The Annals of thoracic surgery, Vol. 72, Issue 4, pp. 1306-10, (2001) (PubMed).

    Wilhelm, Pratschke, Beato, Taal, Kusaka, Hancock, Tilney: "Activation of the heart by donor brain death accelerates acute rejection after transplantation." dans: Circulation, Vol. 102, Issue 19, pp. 2426-33, (2000) (PubMed).

    Carlson, Jansson, Larsson, Bucht, Lorentzen: "The endogenous adjuvant squalene can induce a chronic T-cell-mediated arthritis in rats." dans: The American journal of pathology, Vol. 156, Issue 6, pp. 2057-65, (2000) (PubMed).

    Kraus, Lambracht, Wonigeit, Hünig: "Negative regulation of rat natural killer cell activity by major histocompatibility complex class I recognition." dans: European journal of immunology, Vol. 26, Issue 11, pp. 2582-6, (1997) (PubMed).

  • Antigène
    TCR alpha/beta (T Cell Receptor alpha/beta (TCR alpha/beta))
    Autre désignation
    TCR alpha/beta (TCR alpha/beta Produits)
    Sujet
    The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.,TCRA/B
Vous êtes ici:
Support technique