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CD235a/GYPA anticorps (PE)

GYPA Reactivité: Humain, Rat FACS Hôte: Souris Monoclonal JC159 PE
N° du produit ABIN2749119
  • Antigène Voir toutes CD235a/GYPA (GYPA) Anticorps
    CD235a/GYPA (GYPA) (Glycophorin A (GYPA))
    Reactivité
    • 134
    • 17
    • 12
    • 9
    Humain, Rat
    Hôte
    • 69
    • 67
    • 14
    • 1
    Souris
    Clonalité
    • 93
    • 56
    Monoclonal
    Conjugué
    • 59
    • 14
    • 12
    • 10
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD235a/GYPA est conjugé à/à la PE
    Application
    • 105
    • 58
    • 43
    • 32
    • 26
    • 24
    • 15
    • 13
    • 13
    • 13
    • 13
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    The mouse monoclonal antibody JC159 recognizes an epitope between amino acids 27 and 40 of the extracellular portion of CD235a (glycophorin A), a sialoglycoprotein expressed on early erythroblasts, late erythroblasts, erythroblasts, mature erythrocytes and the cells of erythroid cell lines K562 and HEL. The antibody does not react with glycophorin B.
    Réactivité croisée (Details)
    Human, Rat
    Purification
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogène
    Membrane preparation from splenic hairy cell leukemia
    Clone
    JC159
    Isotype
    IgG1
    Top Product
    Discover our top product GYPA Anticorps primaire
  • Indications d'application
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    Commentaires

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Restrictions
    For Research Use only
  • Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Yamauchi, Takenaka, Urata, Shima, Kikushige, Tokuyama, Iwamoto, Nishihara, Iwasaki, Miyamoto, Honma, Nakao, Matozaki, Akashi: "Polymorphic Sirpa is the genetic determinant for NOD-based mouse lines to achieve efficient human cell engraftment." dans: Blood, Vol. 121, Issue 8, pp. 1316-25, (2013) (PubMed).

    Beck, Jagodzinski, Eller, Thelian, Matyas, Kunz, Alving: "Platelets and erythrocyte-bound platelets bind infectious HIV-1 in plasma of chronically infected patients." dans: PLoS ONE, Vol. 8, Issue 11, pp. e81002, (2013) (PubMed).

    Alijotas-Reig, Palacio-Garcia, Llurba, Vilardell-Tarres: "Cell-derived microparticles and vascular pregnancy complications: a systematic and comprehensive review." dans: Fertility and sterility, Vol. 99, Issue 2, pp. 441-9, (2013) (PubMed).

    Maijenburg, Kleijer, Vermeul, Mul, van Alphen, van der Schoot, Voermans: "The composition of the mesenchymal stromal cell compartment in human bone marrow changes during development and aging." dans: Haematologica, Vol. 97, Issue 2, pp. 179-83, (2012) (PubMed).

  • Antigène
    CD235a/GYPA (GYPA) (Glycophorin A (GYPA))
    Autre désignation
    CD235a (GYPA Produits)
    Synonymes
    anticorps GYPA, anticorps gpa, anticorps AI853584, anticorps CD235a, anticorps GPA, anticorps GPErik, anticorps GPSAT, anticorps HGpMiV, anticorps HGpMiXI, anticorps HGpSta(C), anticorps MN, anticorps MNS, anticorps PAS-2, anticorps glycophorin A (MNS blood group), anticorps glycophorin A, anticorps GYPA, anticorps Gypa
    Sujet
    Glycophorin A (MNS blood group),CD235a (glycophorin A, GPA) is a transmembrane sialoglycoprotein expressed on erythrocytes and their precursors. Similarly to CD235b (glycophorin B, GPB), these molecules provide the cells with a large mucin-like surface, which minimalizes aggregation between erythrocytes in the circulation. GPA is the carrier of blood group M and N specificities, while GPB accounts for S, s and U specificities. CD235a is a receptor of Hsa, a Streptococcus adhesin.,Glycophorin A, GYPA, GPA, PAS-2, Sialoglycoprotein alpha, MN sialoglycoprotein, GPSAT, GPErik, MSN blood group
    ID gène
    2993
    UniProt
    P02724
    Pathways
    Maintenance of Protein Location
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