ALKBH1 anticorps (AA 110-389)

N° du produit ABIN2754901

Détail du produit anti-ALKBH1 anticorps

Antigène: ALKBH1 (AlkB, Alkylation Repair Homolog 1 (ALKBH1))

Épitope: AA 110-389

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALKBH1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Alkylated DNA repair protein alkB homolog 1 protein (110-389AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ALKBH1

Antigène: ALKBH1 (AlkB, Alkylation Repair Homolog 1 (ALKBH1))

Autre désignation: ALKBH1 (ALKBH1 Produits)

Synonymes: anticorps Alkbh, anticorps ABH, anticorps ABH1, anticorps ALKBH, anticorps alkB, anticorps hABH, anticorps 2700073G19Rik, anticorps Abh, anticorps alkB homolog 1, histone H2A dioxygenase, anticorps Alkbh1, anticorps ALKBH1

Sujet:

Background: Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation (By similarity). Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites. DNA lyase activity does not require alpha-ketoglutarate and iron.

Aliases: ABH antibody, ABH1 antibody, alkB antibody, alkB homolog 1 histone H2A dioxygenase antibody, AlkB, alkylation repair homolog 1 (E. coli) antibody, ALKB1_HUMAN antibody, ALKBH antibody, ALKBH1 antibody, Alkylated DNA repair protein alkB homolog 1 antibody, Alkylation repair homolog 1 antibody, Alkylation repair, alkB homolog antibody, Alpha-ketoglutarate-dependent dioxygenase ABH1 antibody, DNA lyase ABH1 antibody, DNA oxidative demethylase ALKBH1 antibody, hABH antibody

UniProt: Q13686

Pathways: Réparation de l'ADN