SGPP2 anticorps

N° du produit ABIN2764173

Détail du produit anti-SGPP2 anticorps

Antigène: SGPP2 (Sphingosine-1-Phosphate Phosphatase 2 (SGPP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SGPP2 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain

Attributs du produit: Sphingosine 1-Phosphate Phosphohydrolase,Sphingosine 1-phosphate (S1P) is a highly bioactive lipid that has a myriad of biological effects both intracellularly as a second messenger and extracellularly by binding to the S1P(1-5)/G-protein-coupled receptors of the endothelial differentiation gene family. Intracellularly, at least two enzymes, sphingosine kinase (1 and 2) and S1P phosphatase, regulate the activity of S1P by governing the phosphorylation of S1P. SPPase2 is localized to the endoplasmic reticulum. The enzymatic activity and localization of SPPase2 are similar to SPPase1. The tissue expression of SPPase2 was different from that of SPPase1. SPPase2 is an important member of the SPPase family which play a role in attenuating intracellular S1P signaling.

Purification: Antigen Immunoaffiinity Purification

Immunogène: Synthetic peptide derived from the sphingosine 1-phosphate phosphatase 2 protein.

Information d'application

Indications d'application: Antibody can be used for Western blotting (1:400 dilution). Tissue lysate should be used at 10-50 μg/lane. Other applications not yet tested. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Stockage

Buffer: Provided as whole antiserum

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur SGPP2

Antigène: SGPP2 (Sphingosine-1-Phosphate Phosphatase 2 (SGPP2))

Autre désignation: Sphingosine 1-Phosphate Phosphatase 2 (SGPP2 Produits)

Synonymes: anticorps SPP2, anticorps RGD1565739, anticorps SPPase2, anticorps Spp2, anticorps sphingosine-1-phosphate phosphatase 2, anticorps sphingosine-1-phosphate phosphotase 2, anticorps SGPP2, anticorps Sgpp2

UniProt: Q8IWX5