CYP46A1 anticorps (C-Term)

N° du produit ABIN2773829

Détail du produit anti-CYP46A1 anticorps

Antigène: CYP46A1 (Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP46A1 est non-conjugé

Application: Western Blotting (WB)

Séquence: YVMGRMDTYF EDPLTFNPDR FGPGAPKPRF TYFPFSLGHR SCIGQQFAQM

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CYP46A1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CYP46A1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 500 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CYP46A1

Antigène: CYP46A1 (Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1))

Autre désignation: CYP46A1 (CYP46A1 Produits)

Synonymes: anticorps CP46, anticorps CYP46, anticorps CYP46A1, anticorps zgc:109896, anticorps MGC147389, anticorps Cyp46, anticorps cytochrome P450 family 46 subfamily A member 1, anticorps cytochrome P450 family 46 subfamily A member 1 L homeolog, anticorps cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1, anticorps cytochrome P450, family 46, anticorps cytochrome P450 46A1, anticorps cytochrome P450, family 46, subfamily a, polypeptide 1, anticorps cholesterol 24-hydroxylase, anticorps cytochrome P450, family 46, subfamily A, polypeptide 1, anticorps CYP46A1, anticorps cyp46a1.L, anticorps cyp46a1.1, anticorps cyp46a1, anticorps PTRG_08343, anticorps PTRG_09667, anticorps Cyp46a1, anticorps Sgly_1093

Sujet: CYP46A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CP46, CYP46
Protein Size: 500

Poids moléculaire: 57 kDa

ID gène: 10858

NCBI Accession: NM_006668, NP_006659

UniProt: Q9Y6A2