TMC8 anticorps (N-Term)
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- Antigène Voir toutes TMC8 Anticorps
- TMC8 (Transmembrane Channel-Like 8 (TMC8))
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Épitope
- N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TMC8 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- PGPTLNLTLQ CPGSRQSPPG VLRFHNQLWH VLTGRAFTNT YLFYGAYRVG
- Homologie
- Human: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against TMC8. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human TMC8
- Top Product
- Discover our top product TMC8 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 726 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- TMC8 (Transmembrane Channel-Like 8 (TMC8))
- Autre désignation
- TMC8 (TMC8 Produits)
- Synonymes
- anticorps EV2, anticorps EVER2, anticorps EVIN2, anticorps Ever2, anticorps mFLJ00400, anticorps transmembrane channel like 8, anticorps transmembrane channel-like 8, anticorps transmembrane channel-like gene family 8, anticorps TMC8, anticorps Tmc8
- Sujet
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Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 8 predicted transmembrane domains and 3 leucine zipper motifs.
Alias Symbols: EV2, EVER2, EVIN2, MGC102701, MGC40121
Protein Interaction Partner: TRAF2, TRAF1,
Protein Size: 726 - Poids moléculaire
- 82 kDa
- ID gène
- 147138
- NCBI Accession
- NM_152468, NP_689681
- UniProt
- Q8IU68
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