APH1B anticorps (C-Term)

N° du produit ABIN2774063

Détail du produit anti-APH1B anticorps

Antigène: APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))

Épitope: C-Term

Reactivité: Souris, Humain, Rat, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APH1B est non-conjugé

Application: Western Blotting (WB)

Séquence: YYGINLASAF IILVLMGTWA FLAAGGSCRS LKLCLLCQDK NFLLYNQRSR

Homologie: Cow: 77%, Dog: 85%, Guinea Pig: 92%, Horse: 77%, Human: 100%, Mouse: 92%, Rabbit: 85%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against APH1B. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 216 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur APH1B

Antigène: APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))

Autre désignation: APH1B (Aph1b Produits)

Synonymes: anticorps APH-1B, anticorps PRO1328, anticorps PSFL, anticorps TAAV688, anticorps APH-1B', anticorps 2310057K14Rik, anticorps Aph1c, anticorps aph-1 homolog B, gamma-secretase subunit, anticorps aph-1 homolog B, gamma secretase subunit, anticorps aph1 homolog B, gamma secretase subunit, anticorps APH1B, anticorps Aph1b

Sujet: This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein.
Alias Symbols: APH-1B, DKFZp564D0372, FLJ33115, PRO1328, PSFL, TAAV688
Protein Interaction Partner: UBC, PSENEN, NCSTN, PSEN2, PSEN1,
Protein Size: 216

Poids moléculaire: 23 kDa

ID gène: 83464

NCBI Accession: NM_001145646, NP_001139118

UniProt: Q564N3

Pathways: Signalisation Notch, Neurotrophin Signaling Pathway