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NFKBIZ anticorps (C-Term)

NFKBIZ Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Chévre, Cobaye, Mouton, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2774196
  • Antigène Voir toutes NFKBIZ Anticorps
    NFKBIZ (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, zeta (NFKBIZ))
    Épitope
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 15
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Chévre, Cobaye, Mouton, Poisson zèbre (Danio rerio)
    Hôte
    • 17
    • 1
    Lapin
    Clonalité
    • 17
    • 1
    Polyclonal
    Conjugué
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NFKBIZ est non-conjugé
    Application
    • 11
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    VRLLMRKGAD PSTRNLENEQ PVHLVPDGPV GEQIRRILKG KSIQQRAPPY
    Homologie
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 91%
    Attributs du produit
    This is a rabbit polyclonal antibody against Nfkbiz. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide corresponding to a region of Mouse
    Top Product
    Discover our top product NFKBIZ Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 728 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    NFKBIZ (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, zeta (NFKBIZ))
    Autre désignation
    Nfkbiz (NFKBIZ Produits)
    Synonymes
    anticorps RGD1310834, anticorps NFKBIZ, anticorps MAIL, anticorps AA408868, anticorps INAP, anticorps Mail, anticorps IKBZ, anticorps NFKB inhibitor zeta, anticorps nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta, anticorps nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta, anticorps Nfkbiz, anticorps NFKBIZ, anticorps nfkbiz
    Sujet
    Nfkbiz is involved in regulation of NF-kappa-B transcription factor complexes. It inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation. It inhibits DNA-binding of RELA and NFKB1/p50, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer. It seems also to activate NF-kappa-B-mediated transcription. In vitro, upon association with NFKB1/p50, Nfkbiz has transcriptional activation activity and, together with NFKB1/p50 and RELA, Nfkbiz is recruited to LCN2 promoters.
    Alias Symbols: AA408868, INAP, Mail
    Protein Interaction Partner: Nfkb2, Nfkb1, Ikbkg, Elf5, Ehf, Il6,
    Protein Size: 728
    Poids moléculaire
    80 kDa
    ID gène
    80859
    NCBI Accession
    NM_030612, NP_085115
    UniProt
    Q9EST8
    Pathways
    Signalisation NF-kappaB
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