Caspase 3 anticorps (N-Term)
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- Antigène Voir toutes Caspase 3 (CASP3) Anticorps
- Caspase 3 (CASP3)
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Épitope
- N-Term
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Reactivité
- Humain, Rat, Boeuf (Vache), Chien, Porc, Lapin, Cobaye, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Caspase 3 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- MENTENSVDS KSIKNLEPKI IHGSESMDSG ISLDNSYKMD YPEMGLCIII
- Homologie
- Cow: 84%, Dog: 84%, Guinea Pig: 84%, Horse: 92%, Human: 100%, Pig: 92%, Rabbit: 84%, Rat: 84%
- Attributs du produit
- This is a rabbit polyclonal antibody against CASP3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human CASP3
- Top Product
- Discover our top product CASP3 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 277 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Bone Marrow Culture-Derived Conditioned Medium Recovers Endothelial Function of Vascular Grafts following In Vitro Ischemia/Reperfusion Injury in Diabetic Rats." dans: Stem cells international, Vol. 2022, pp. 7019088, (2022) (PubMed).
: "A scaffold-free surface culture of B16F10 murine melanoma cells based on magnetic levitation." dans: Cytotechnology, Vol. 68, Issue 6, pp. 2323-2334, (2016) (PubMed).
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Bone Marrow Culture-Derived Conditioned Medium Recovers Endothelial Function of Vascular Grafts following In Vitro Ischemia/Reperfusion Injury in Diabetic Rats." dans: Stem cells international, Vol. 2022, pp. 7019088, (2022) (PubMed).
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- Antigène
- Caspase 3 (CASP3)
- Autre désignation
- CASP3 (CASP3 Produits)
- Synonymes
- anticorps CPP32, anticorps CPP32B, anticorps SCA-1, anticorps A830040C14Rik, anticorps AC-3, anticorps Apopain, anticorps CC3, anticorps Caspase-3, anticorps Lice, anticorps Yama, anticorps mldy, anticorps xcpp32, anticorps casp3, anticorps zgc:100890, anticorps CASP-3, anticorps caspase-3, anticorps caspase 3, anticorps caspase 3 S homeolog, anticorps caspase 3, apoptosis-related cysteine peptidase a, anticorps caspase 3, apoptosis-related cysteine peptidase, anticorps CASP3, anticorps Casp3, anticorps casp3.S, anticorps casp3a
- Sujet
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CASP3 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
Alias Symbols: CPP32, SCA-1, CPP32B
Protein Interaction Partner: BAX, PARP1, PTGES3, XIAP, CRYAB, BIRC7, UBC, MDM2, Gzmb, VIM, STAT1, SPTAN1, ROCK1, GSN, DFFA, CASP9, CASP7, CASP6, CASP2, BID, ARHGDIA, TNFSF10, PLA2G4B, CDKN1A, RB1, PRKDC, GLRX, GATA1, SOCS5, YWHAG, MAPK9, MAPK8, SP1, PKN1, CASP8, BIRC3, BIRC2, ZBTB16,
Protein Size: 277 - Poids moléculaire
- 32 kDa
- ID gène
- 836
- NCBI Accession
- NM_004346, NP_004337
- UniProt
- P42574
- Pathways
- Apoptose, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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