NR2F2 anticorps (N-Term)
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- Antigène Voir toutes NR2F2 Anticorps
- NR2F2 (Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Chien, Porc, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NR2F2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- AMVVSTWRDP QDEVPGSQGS QASQAPPVPG PPPGAPHTPQ TPGQGGPAST
- Réactivité croisée
- Boeuf (Vache), Chien, Poulet, Humain, Souris, Rat (Rattus)
- Homologie
- Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against NR2F2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human NR2F2
- Top Product
- Discover our top product NR2F2 Anticorps primaire
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- Indications d'application
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WB Suggested Anti-NR2F2 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:62500
Positive Control: Human brain.
Optimal working dilutions should be determined experimentally by the investigator. - Commentaires
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Antigen size: 414 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- NR2F2 (Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2))
- Autre désignation
- NR2F2 (NR2F2 Produits)
- Synonymes
- anticorps nr2f2, anticorps MGC52954, anticorps ARP1, anticorps COUPTFB, anticorps COUPTFII, anticorps NF-E3, anticorps NR2F1, anticorps SVP40, anticorps TFCOUP2, anticorps 2700033K02Rik, anticorps 9430015G03Rik, anticorps ARP-1, anticorps Aporp1, anticorps COUP-TF2, anticorps COUP-TFII, anticorps EAR3, anticorps Tcfcoup2, anticorps Tfcoup2, anticorps fc94g08, anticorps svp40, anticorps svp[40], anticorps wu:fc94g08, anticorps nuclear receptor subfamily 2 group F member 2 L homeolog, anticorps Nr2f2 protein, anticorps nuclear receptor subfamily 2 group F member 2, anticorps nuclear receptor subfamily 2, group F, member 2, anticorps nr2f2.L, anticorps nr2f2, anticorps NR2F2, anticorps Nr2f2
- Sujet
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NR2F2, an orphan member of the nuclear hormone receptor superfamily, acts as a transcriptional repressor by antagonizing the functions of other nuclear hormone receptors and by actively silencing transcription. However, in certain contexts, NR2F2 stimulates transcription directly. NR2F2, MyoD and p300 interact in a competitive manner, and that increasing amounts of NR2F2 have the ability to reduce the interaction between myoD and p300 invitro. NR2F2 post-transcriptionally regulates myoD activity/function, and that crosstalk between orphan nuclear receptors and the myogenic bHLH proteins has functional consequences for differentiation.
Alias Symbols: ARP1, COUP-TFII, COUPTFB, MGC117452, SVP40, TFCOUP2, NF-E3, NR2F1, COUPTFII
Protein Interaction Partner: NSD1, BCL11A, NR2F2, BIK, SETD7, FAM46A, HIPK3, UBC, TFAP4, Cebpb, SMARCAD1, NR2F6, POU5F1, NR3C1, PHB2, TRIP4, PIAS1, BCL11B, TRIM24, EP300, SQSTM1, HDAC1, NCOR2, MYOD1, LCK,
Protein Size: 414 - Poids moléculaire
- 45 kDa
- ID gène
- 7026
- NCBI Accession
- NM_021005, NP_066285
- UniProt
- P24468
- Pathways
- Steroid Hormone Mediated Signaling Pathway
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