HERC6 anticorps (N-Term)

N° du produit ABIN2774750

Détail du produit anti-HERC6 anticorps

Antigène: HERC6 (HECT and RLD Domain Containing E3 Ubiquitin Protein Ligase Family Member 6 (HERC6))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Porc, Lapin, Boeuf (Vache), Cheval, Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HERC6 est non-conjugé

Application: Western Blotting (WB)

Séquence: LSKDSQVFSW GKNSHGQLGL GKEFPSQASP QRVRSLEGIP LAQVAAGGAH

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against HERC6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human HERC6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1022 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HERC6

Antigène: HERC6 (HECT and RLD Domain Containing E3 Ubiquitin Protein Ligase Family Member 6 (HERC6))

Autre désignation: HERC6 (HERC6 Produits)

Synonymes: anticorps 1700121D12Rik, anticorps 2510038N07Rik, anticorps 4930427L17Rik, anticorps AI451296, anticorps CEB1, anticorps Herc5, anticorps HECT and RLD domain containing E3 ubiquitin protein ligase family member 6, anticorps hect domain and RLD 6, anticorps HERC6, anticorps Herc6

Sujet: HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).
Alias Symbols: FLJ20637
Protein Interaction Partner: FUS, UBC, HSP90AA1, UBQLN2, HERC4, HERC3, NME2,
Protein Size: 1022

Poids moléculaire: 115 kDa

ID gène: 55008

NCBI Accession: NM_017912, NP_060382

UniProt: Q8IVU3