NKRF anticorps (N-Term)

N° du produit ABIN2774943

Détail du produit anti-NKRF anticorps

Antigène: NKRF (NFKB Repressing Factor (NKRF))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Cheval, Lapin, Boeuf (Vache), Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NKRF est non-conjugé

Application: Western Blotting (WB)

Séquence: HFVASSSKDE RQEDPYGPQT KEVNEQTHFA SMPRDIYQDY TQDSFSIQDG

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 92%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against NKRF. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human NKRF

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 690 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NKRF

Antigène: NKRF (NFKB Repressing Factor (NKRF))

Autre désignation: NKRF (NKRF Produits)

Synonymes: anticorps NKRF, anticorps NRF, anticorps nrf, anticorps itba4, anticorps 9430034D17Rik, anticorps AW124770, anticorps C80287, anticorps ITBA4, anticorps RGD1563950, anticorps NFKB repressing factor, anticorps NFKB repressing factor L homeolog, anticorps NF-kappaB repressing factor, anticorps NFKB repressing factor-like, anticorps NKRF, anticorps nkrf, anticorps nkrf.L, anticorps Nkrf, anticorps Nkrfl

Sujet: This protein Interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcriptionThis gene encodes a transcription factor that interacts with specific negative regulatory elements (NREs) to mediate transcriptional repression of certain NK-kappa-B-responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm.
Alias Symbols: ITBA4, NRF
Protein Interaction Partner: STAU1, UBC, XRN2, BMI1, TARDBP, BARD1, CAND1, COPS5, CUL1, CUL3, SIRT7, HNRNPA1, SUMO2, VHL, DHX58, PRKRA, SUMO1, HMOX2, BCL6, REL, RELA, NFKB2, NFKB1,
Protein Size: 690

Poids moléculaire: 78 kDa

ID gène: 55922

NCBI Accession: NM_017544, NP_060014

UniProt: A3F768