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DPF3 anticorps (Middle Region)

DPF3 Reactivité: Humain, Souris, Rat, Lapin, Cobaye, Cheval, Boeuf (Vache), Chien WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2775708
  • Antigène Voir toutes DPF3 Anticorps
    DPF3 (D4, Zinc and Double PHD Fingers, Family 3 (DPF3))
    Épitope
    • 15
    • 7
    • 6
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 31
    • 23
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat, Lapin, Cobaye, Cheval, Boeuf (Vache), Chien
    Hôte
    • 46
    Lapin
    Clonalité
    • 46
    Polyclonal
    Conjugué
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DPF3 est non-conjugé
    Application
    • 39
    • 18
    • 13
    • 13
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Séquence
    KDGFTSESTT LEALLRGEGV EKKVDAREEE SIQEIQRVLE NDENVEEGNE
    Homologie
    Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against DPF3. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human DPF3
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 357 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Theodorou, Speletas, Mamara, Papachristopoulou, Lazou, Scorilas, Katsantoni: "Identification of a STAT5 target gene, Dpf3, provides novel insights in chronic lymphocytic leukemia." dans: PLoS ONE, Vol. 8, Issue 10, pp. e76155, (2013) (PubMed).

    Hoyal, Kammerer, Roth, Reneland, Marnellos, Kiechle, Schwarz-Boeger, Griffiths, Ebner, Rehbock, Nelson, Braun: "Genetic polymorphisms in DPF3 associated with risk of breast cancer and lymph node metastases." dans: Journal of carcinogenesis, Vol. 4, pp. 13, (2005) (PubMed).

  • Antigène
    DPF3 (D4, Zinc and Double PHD Fingers, Family 3 (DPF3))
    Autre désignation
    DPF3 (DPF3 Produits)
    Synonymes
    anticorps BAF45C, anticorps CERD4, anticorps 2810403B03Rik, anticorps 6530402L11Rik, anticorps C78788, anticorps cer-d4, anticorps si:ch211-268e23.1, anticorps wu:fj43h12, anticorps double PHD fingers 3, anticorps D4, zinc and double PHD fingers, family 3, anticorps DPF3, anticorps Dpf3, anticorps dpf3
    Sujet
    DPF3 is a muscle-specific component of the BAF complex, a multiprotein complex involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). DPF3 specifically binds acetylated lysines on histone 3 and 4 (H3K14ac, H3K9ac, H4K5ac, H4K8ac, H4K12ac, H4K16ac). In the complex, it acts as a tissue-specific anchor between histone acetylations and methylations and chromatin remodeling. It thereby probably plays an essential role in heart and skeletal muscle development.
    Alias Symbols: CERD4, FLJ14079
    Protein Interaction Partner: SMARCA4, SMARCA2, RELA, NFKB1, SMARCD1, SMARCC1, SMARCB1, ESRRA,
    Protein Size: 357
    Poids moléculaire
    40 kDa
    ID gène
    8110
    NCBI Accession
    NM_012074, NP_036206
    UniProt
    Q92784
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