KCNN1 anticorps (C-Term)

N° du produit ABIN2776145

Détail du produit anti-KCNN1 anticorps

Antigène: KCNN1 (Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 1 (KCNN1))

Épitope: C-Term

Reactivité: Humain, Rat, Cobaye, Boeuf (Vache), Chien, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNN1 est non-conjugé

Application: Western Blotting (WB)

Séquence: KIEQGKLNDQ ANTLTDLAKT QTVMYDLVSE LHAQHEELEA RLATLESRLD

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 79%, Horse: 92%, Human: 100%, Pig: 93%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against KCNN1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human KCNN1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 543 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-KCNN1 (ABIN2776145)

Arnold, Mühlen: "The influence of the thickness of non-piezoelectric pieces on pre-stressed piezotransducers." dans: Ultrasonics, Vol. 41, Issue 3, pp. 191-6, (2003) (PubMed).

Détails sur KCNN1

Antigène: KCNN1 (Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 1 (KCNN1))

Autre désignation: KCNN1 (KCNN1 Produits)

Synonymes: anticorps KCNN1, anticorps kcnn1, anticorps si:ch211-200a16.1, anticorps sk1, anticorps hsk1, anticorps skca1, anticorps MGC145919, anticorps KCa2.1, anticorps SK1, anticorps SKCA1, anticorps hSK1, anticorps AI854248, anticorps potassium calcium-activated channel subfamily N member 1, anticorps potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1b, anticorps potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1, anticorps small conductance calcium-activated potassium channel protein 1, anticorps potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1, anticorps KCNN1, anticorps kcnn1b, anticorps kcnn1, anticorps LOC100456154, anticorps Kcnn1

Sujet: Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. KCNN1 is a member of the KCNN family of potassium channels.
Alias Symbols: SK1, hSK1, SKCA1, KCa2.1
Protein Interaction Partner: UBC,
Protein Size: 543

Poids moléculaire: 60 kDa

ID gène: 3780

NCBI Accession: NM_002248, NP_002239

UniProt: Q6DJU4