P2RX1 anticorps (Middle Region)

N° du produit ABIN2776150

Détail du produit anti-P2RX1 anticorps

Antigène: P2RX1 (Purinergic Receptor P2X, Ligand Gated Ion Channel 1 (P2RX1))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Lapin, Chien, Boeuf (Vache), Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp P2RX1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: VVGITIDWHC DLDWHVRHCR PIYEFHGLYE EKNLSPGFNF RFARHFVENG

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against P2RX1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human P2RX1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 399 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur P2RX1

Antigène: P2RX1 (Purinergic Receptor P2X, Ligand Gated Ion Channel 1 (P2RX1))

Autre désignation: P2RX1 (P2RX1 Produits)

Synonymes: anticorps p2xr1, anticorps P2X1, anticorps AI323649, anticorps BB122383, anticorps P2x, anticorps Pdcd3, anticorps RP-2, anticorps P2XMR, anticorps P2X1R, anticorps purinergic receptor P2X, ligand-gated ion channel, 1, anticorps purinergic receptor P2X 1, anticorps calcium/calmodulin dependent protein kinase kinase 1, anticorps p2rx1, anticorps P2RX1, anticorps P2rx1, anticorps CAMKK1

Sujet: P2RX1 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.
Alias Symbols: P2X1
Protein Interaction Partner: P2RX2,
Protein Size: 399

Poids moléculaire: 45 kDa

ID gène: 5023

NCBI Accession: NM_002558, NP_002549

UniProt: P51575

Pathways: Positive Regulation of Endopeptidase Activity