VDAC2 anticorps (N-Term)

N° du produit ABIN2776154

Détail du produit anti-VDAC2 anticorps

Antigène: VDAC2 (Voltage-Dependent Anion Channel 2 (VDAC2))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye, Poisson zèbre (Danio rerio), Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VDAC2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MATHGQTCAR PMCIPPSYAD LGKAARDIFN KGFGFGLVKL DVKTKSCSGV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 79%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against VDAC2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human VDAC2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 294 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-VDAC2 (ABIN2776154)

Hrabakova, Kollareddy, Tyleckova, Halada, Hajduch, Gadher, Kovarova: "Cancer cell resistance to aurora kinase inhibitors: identification of novel targets for cancer therapy." dans: Journal of proteome research, Vol. 12, Issue 1, pp. 455-69, (2013) (PubMed).

Détails sur VDAC2

Antigène: VDAC2 (Voltage-Dependent Anion Channel 2 (VDAC2))

Autre désignation: VDAC2 (VDAC2 Produits)

Synonymes: anticorps POR, anticorps Vdac6, anticorps mVDAC2, anticorps mVDAC6, anticorps wu:fa01a08, anticorps wu:fa98a10, anticorps wu:fb50g11, anticorps zgc:55795, anticorps zgc:77621, anticorps vdac2, anticorps VDAC2, anticorps ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 2, anticorps ATVDAC2, anticorps K9I9.6, anticorps K9I9_6, anticorps voltage dependent anion channel 2, anticorps voltage dependent anion channel 2, anticorps voltage-dependent anion channel 2, anticorps voltage-dependent anion channel 2 S homeolog, anticorps VDAC2, anticorps Vdac2, anticorps vdac2, anticorps vdac2.S

Sujet: VDAC2 forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective.
Alias Symbols: RP11-375G3.1, FLJ23841, POR
Protein Interaction Partner: MDM2, ADRB2, FBXO6, PARK2, PHKG2, PHB, VCAM1, UBC, ITGA4, FN1, ATF2, env, MDC1, ECT2, ACAA2, TRAP1, ATP6V1F, VDAC3, VDAC1, UBE2L3, UBA52, SSBP1, SCP2, RPN1, MPV17, RPSA, HNRNPU, FLOT2, ELAVL1, DDOST, APP, Htt, ZNF454, SFXN3, THOC6, SUGP1, SEPT11, ZFR, ATP
Protein Size: 294

Poids moléculaire: 32 kDa

ID gène: 7417

NCBI Accession: NM_003375, NP_003366