P2RX7 anticorps (N-Term)
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- Antigène Voir toutes P2RX7 Anticorps
- P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp P2RX7 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- IQSMNYGTIK WFFHVIIFSY VCFALVSDKL YQRKEPVISS VHTKVKGIAE
- Homologie
- Cow: 93%, Dog: 79%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against P2RX7. It was validated on Western Blot and immunohistochemistry.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human P2RX7
- Top Product
- Discover our top product P2RX7 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 595 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Extracellular nucleotides as novel, underappreciated pro-metastatic factors that stimulate purinergic signaling in human lung cancer cells." dans: Molecular cancer, Vol. 14, pp. 201, (2015) (PubMed).
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Extracellular nucleotides as novel, underappreciated pro-metastatic factors that stimulate purinergic signaling in human lung cancer cells." dans: Molecular cancer, Vol. 14, pp. 201, (2015) (PubMed).
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- Antigène
- P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
- Autre désignation
- P2RX7 (P2RX7 Produits)
- Synonymes
- anticorps p2xr7, anticorps P2RX7, anticorps P2X7, anticorps AI467586, anticorps P2X(7), anticorps P2X7R, anticorps p2x7, anticorps purinergic receptor P2X 7, anticorps purinergic receptor P2X, ligand-gated ion channel, 7, anticorps P2X purinoceptor 7, anticorps P2RX7, anticorps p2rx7, anticorps LOC100458463, anticorps P2rx7
- Sujet
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The product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression.
Alias Symbols: P2X7
Protein Interaction Partner: KRTAP10-8, KRT31, TM9SF1, CASK, EFNB3, EMP3, PANX1, SVIL, ACTB,
Protein Size: 595 - Poids moléculaire
- 69 kDa
- ID gène
- 5027
- UniProt
- Q99572
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
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