Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (N-Term) anticorps

Détails pour le produit réf. ABIN2776586
Antigène
  • C1
  • C2
  • HNRNP
  • HNRPC
  • SNRPC
  • MGC53243
  • HNRNPC
  • bZ1G18.4
  • fb57h12
  • fi16b11
  • wu:fb57h12
  • wu:fi16b11
  • zgc:55701
  • AL022939
  • D14Wsu171e
  • Hnrpc
  • Hnrpc1
  • Hnrpc2
  • hnRNPC1
  • hnRNPC2
  • hnrnp-C
  • hnRNP C
  • hnrnp
  • hnrpc
  • snrpc
  • heterogeneous nuclear ribonucleoprotein C (C1/C2)
  • heterogeneous nuclear ribonucleoprotein C (C1/C2) S homeolog
  • heterogeneous nuclear ribonucleoprotein C
  • heterogeneous nuclear ribonucleoprotein C (C1/C2) L homeolog
  • HNRNPC
  • hnrnpc.S
  • hnrnpc
  • Hnrnpc
  • hnrnpc.L
Épitope
N-Term
28
10
8
5
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivité
Chien, Humain, Souris, Porc, Lapin, Rat (Rattus)
137
78
78
15
11
11
8
8
7
7
6
5
5
5
3
1
Hôte
Lapin
127
11
Clonalité
Polyclonal
Conjugué
Inconjugué
6
4
4
4
4
4
4
3
3
2
2
2
1
1
1
1
1
Application
Western Blotting (WB)
103
54
53
35
33
13
11
8
6
4
1
1
1
Options
Immunogène The immunogen is a synthetic peptide directed towards the N terminal region of human HNRPC
Blocking Peptide Blocking peptide for this product available: ABIN978104
Séquence LDINLAAEPK VNRGKAGVKR SAAEMYGSVT EHPSPSPLLS SSFDLDYDFQ
Homologie Dog: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%
Attributs du produit This is a rabbit polyclonal antibody against HNRPC. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Antigène
Autre désignation HNRPC (HNRNPC Antibody Extrait)
Sujet HNRPC belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein can act as a tetramer and is involved in the assembly of 40S hnRNP particles.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has one RRM domain that binds to RNAs. Two alternatively spliced transcript variants have been described for this gene.
Alias Symbols: C1, C2, HNRNP, MGC104306, MGC105117, MGC117353, MGC131677, SNRPC, hnRNPC, HNRPC
Protein Interaction Partner: SUMO1P1, RALYL, RBM41, ZFYVE26, SUMO1, UBE2I, UBC, SDCBP, LMO2, KPNA4, KPNA3, KPNA2, HNRNPC, EPS8, BRIP1, PALB2, BRCA2, BRCA1, BARD1, CEP250, SUMO2, SUMO3, RAD51, IVNS1ABP, STAU1, MDM2, ERG, EED, RNF2, rev, CDKN2A, PARK2, SRPK2, SRPK1, CLK3, TARDBP, YWHAQ
Protein Size: 303
Poids moléculaire 33 kDa
ID gène 3183
NCBI Accession NM_031314, NP_112604
UniProt P07910
Indications d'application Optimal working dilutions should be determined experimentally by the investigator.
Commentaires

Antigen size: 303 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freeze-thaw cycles.
Stock -20 °C
Stockage commentaire For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Images (Fournisseur)
Western Blotting (WB) image for anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (N-Term) antibody (ABIN2776586) WB Suggested Anti-HNRPC Antibody Titration: 0.2-1 ug/ml Positive Control: Jurkat c...
Produit citée dans: Hayakawa, Fujikane, Ito, Matsumoto, Nakayama, Sekiguchi: "Human proteins that specifically bind to 8-oxoguanine-containing RNA and their responses to oxidative stress." dans: Biochemical and biophysical research communications, Vol. 403, Issue 2, pp. 220-4, 2010 (PubMed).

Background publications Rual, Venkatesan, Hao, Hirozane-Kishikawa, Dricot, Li, Berriz, Gibbons, Dreze, Ayivi-Guedehoussou, Klitgord, Simon, Boxem, Milstein, Rosenberg, Goldberg, Zhang, Wong, Franklin, Li, Albala, Lim et al.: "Towards a proteome-scale map of the human protein-protein interaction network. ..." dans: Nature, Vol. 437, Issue 7062, pp. 1173-8, 2005 (PubMed).

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