CYP2E1 anticorps (C-Term)

N° du produit ABIN2776801

Détail du produit anti-CYP2E1 anticorps

Antigène: CYP2E1 (Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Lapin, Chien, Cheval, Cobaye, Mouton, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP2E1 est non-conjugé

Application: Western Blotting (WB)

Séquence: QEFPDPEKFK PEHFLNENGK FKYSDYFKPF STGKRVCAGE GLARMELFLL

Homologie: Cow: 79%, Dog: 86%, Guinea Pig: 92%, Horse: 79%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 92%, Sheep: 79%

Attributs du produit: This is a rabbit polyclonal antibody against CYP2E1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CYP2E1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 493 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CYP2E1

Antigène: CYP2E1 (Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1))

Autre désignation: CYP2E1 (CYP2E1 Produits)

Synonymes: anticorps CYP2E1, anticorps CYP2E, anticorps CYPIIE1, anticorps CPE1, anticorps P450-J, anticorps P450C2E, anticorps Cyp2e, anticorps cytochrome P450, family 2, subfamily E, polypeptide 1, anticorps cytochrome P450 2E1, anticorps cytochrome P450 2E1-like, anticorps cytochrome P450 family 2 subfamily E member 1, anticorps cytochrome P450, family 2, subfamily e, polypeptide 1, anticorps CYP2E1, anticorps PTRG_07411, anticorps LOC100342572, anticorps LOC100727914, anticorps LOC101843716, anticorps Cyp2e1

Sujet: CYP2E1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.
Alias Symbols: CPE1, CYP2E, P450-J, P450C2E
Protein Interaction Partner: UBC, ABCA5, LAMC3, NMI, PTN, POR, MAFG, GATM, ECHS1, CYB5A, AGXT2, RPL13A, CLU, STUB1, AMFR, FANCG,
Protein Size: 493

Poids moléculaire: 54 kDa

ID gène: 1571

NCBI Accession: NM_000773, NP_000764

UniProt: P05181