ABCB4 anticorps (N-Term)

N° du produit ABIN2776966

Détail du produit anti-ABCB4 anticorps

Antigène: ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cheval, Mouton, Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCB4 est non-conjugé

Application: Western Blotting (WB)

Séquence: AGAVAEEALG AIRTVIAFGG QNKELERYQK HLENAKEIGI KKAISANISM

Homologie: Cow: 86%, Dog: 77%, Guinea Pig: 77%, Horse: 77%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%, Sheep: 77%

Attributs du produit: This is a rabbit polyclonal antibody against ABCB4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ABCB4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1279 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ABCB4

Antigène: ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4))

Autre désignation: ABCB4 (ABCB4 Produits)

Synonymes: anticorps ABC21, anticorps GBD1, anticorps ICP3, anticorps MDR2, anticorps MDR2/3, anticorps MDR3, anticorps PFIC-3, anticorps PGY3, anticorps zgc:172149, anticorps Mdr2, anticorps Pgy-2, anticorps Pgy2, anticorps mdr-2, anticorps Pgy3, anticorps ABCB4a, anticorps DEFB1, anticorps PGP2, anticorps PGY2, anticorps PGP3, anticorps ABCB4, anticorps RUNDC3B, anticorps ATP binding cassette subfamily B member 4, anticorps ATP-binding cassette, sub-family B (MDR/TAP), member 4, anticorps beta-defensin 1-like, anticorps ATP-binding cassette, sub-family B (MDR/TAP), member 1B, anticorps RUN domain-containing protein 3B, anticorps ABCB4, anticorps abcb4, anticorps Abcb4, anticorps LOC100861170, anticorps Abcb1b, anticorps LOC101122517

Sujet: ABCB4, a membrane-associated protein, is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. ABCB4 is a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined, however, it may involve transport of phospholipids from liver hepatocytes into bile.The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined, however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.
Alias Symbols: ABC21, GBD1, MDR2, MDR2/3, MDR3, PFIC-3, PGY3
Protein Interaction Partner: PIGY, TESK1, HAX1,
Protein Size: 1279

Poids moléculaire: 141 kDa

ID gène: 5244

NCBI Accession: NM_000443, NP_000434

UniProt: A4D1D4

Pathways: Regulation of Lipid Metabolism by PPARalpha