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TNNT1 anticorps (Middle Region)

TNNT1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2777153
  • Antigène Voir toutes TNNT1 Anticorps
    TNNT1 (Slow Skeletal Troponin T (TNNT1))
    Épitope
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 26
    • 13
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)
    Hôte
    • 24
    • 6
    • 1
    Lapin
    Clonalité
    • 27
    • 4
    Polyclonal
    Conjugué
    • 19
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TNNT1 est non-conjugé
    Application
    • 24
    • 11
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    WIHQLESEKF DLMAKLKQQK YEINVLYNRI SHAQKFRKGA GKGRVGGRWK
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 85%
    Attributs du produit
    This is a rabbit polyclonal antibody against TNNT1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human TNNT1
    Top Product
    Discover our top product TNNT1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 278 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    TNNT1 (Slow Skeletal Troponin T (TNNT1))
    Autre désignation
    TNNT1 (TNNT1 Produits)
    Synonymes
    anticorps ANM, anticorps NEM5, anticorps STNT, anticorps TNT, anticorps TNTS, anticorps TNNI1, anticorps AW146156, anticorps Tnt, anticorps sTnT, anticorps ssTnT, anticorps Fang2, anticorps tnTs, anticorps Tnnt, anticorps zgc:193831, anticorps zgc:193865, anticorps troponin T1, slow skeletal type, anticorps troponin I1, slow skeletal type, anticorps troponin T1, skeletal, slow, anticorps troponin T1, slow skeletal type S homeolog, anticorps troponin T type 1 (skeletal, slow), anticorps TNNT1, anticorps TNNI1, anticorps Tnnt1, anticorps tnnt1.S, anticorps tnnt1
    Sujet
    TNNT1 is a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year.This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: ANM, MGC104241, TNT, STNT, TNTS
    Protein Interaction Partner: CCDC136, TFIP11, LDOC1, MORF4L1, TBPL1, TPM3, TPM1, TNNT1, NFE2L2, KRT40, UBC, PI4KA, SERPINA4, OSM, MARS, HSP90AB1, FYN, EEF1G, DDX5, CHD3, BLOC1S2, C2orf44, ZNF768, ZNF250, ZC3H15, NAGK, HMP19, TRA2A, TMEM98, ARMC8, OSBP2, ZKSCAN5, LARP1, NACAD, SNW1, S
    Protein Size: 278
    Poids moléculaire
    33 kDa
    ID gène
    7138
    NCBI Accession
    NM_003283, NP_003274
    UniProt
    P13805
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