PPFIBP1 anticorps (N-Term)

N° du produit ABIN2777159

Détail du produit anti-PPFIBP1 anticorps

Antigène: PPFIBP1 (PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Chien, Cobaye, Porc, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPFIBP1 est non-conjugé

Application: Western Blotting (WB)

Séquence: PFMGSLRALH LVEDLRGLLE MMETDEKEGL RCQIPDSTAE TLVEWLQSQM

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against PPFIBP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PPFIBP1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 170 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PPFIBP1

Antigène: PPFIBP1 (PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1))

Autre désignation: PPFIBP1 (PPFIBP1 Produits)

Synonymes: anticorps liprin-beta-1, anticorps L2, anticorps SGT2, anticorps hSGT2, anticorps hSgt2p, anticorps 4632409B19Rik, anticorps AW214454, anticorps AW261454, anticorps PPFIA binding protein 1, anticorps PTPRF interacting protein, binding protein 1 (liprin beta 1), anticorps PTPRF interacting protein, binding protein 1 (liprin beta 1) S homeolog, anticorps Ppfibp1, anticorps ppfibp1, anticorps ppfibp1.S, anticorps PPFIBP1

Sujet: PPFIBP1 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis.The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: L2, hSGT2, hSgt2p, SGT2
Protein Interaction Partner: VCP, TP53, CDKN1A, CEP76, CEP250, LATS2, YWHAQ, YWHAB, UBC, GRK5, SH3KBP1, ELAVL1, YWHAG, S100A4, PPFIA1, PPFIA3, PPFIA2, PPFIBP1, PTPRM, SFN,
Protein Size: 170

Poids moléculaire: 19 kDa

ID gène: 8496

NCBI Accession: NM_177444, NP_803193