E2F1 anticorps (Middle Region)
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- Antigène Voir toutes E2F1 Anticorps
- E2F1 (E2F Transcription Factor 1 (E2F1))
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Épitope
- Middle Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp E2F1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- LCPEETVGGI SPGKTPSQEV TSEEENRATD SATIVSPPPS SPPSSLTTDP
- Homologie
- Human: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against E2F1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product E2F1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 437 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- E2F1 (E2F Transcription Factor 1 (E2F1))
- Autre désignation
- E2F1 (E2F1 Produits)
- Synonymes
- anticorps CG6376, anticorps DRTF1/E2F, anticorps DmE2F-1, anticorps Dmel\\CG6376, anticorps Dp, anticorps E(Sev-CycE)3A, anticorps E(var)3-93E, anticorps E(var)3-95E, anticorps E(var)93E, anticorps E2F, anticorps E2F-1, anticorps E2F1, anticorps E2f1, anticorps Evar(3)164, anticorps dE2F, anticorps dE2F1, anticorps dE2f, anticorps dE2f1, anticorps de2f1, anticorps def21, anticorps drosE2F1, anticorps e2f, anticorps e2f1, anticorps l(3)07172, anticorps l(3)j3B1, anticorps l(3)j3C2, anticorps l(3)rM729, anticorps RBAP1, anticorps RBBP3, anticorps RBP3, anticorps mKIAA4009, anticorps xE2F, anticorps ATE2FB, anticorps E2F TRANSCRIPTION FACTOR-1 E2F1, anticorps E2F transcription factor 1, anticorps E2FB, anticorps E2FB TRANSCRIPTION FACTOR, anticorps E2F transcription factor 1, anticorps E2F transcription factor 1 L homeolog, anticorps E2f1, anticorps E2F1, anticorps e2f1.L
- Sujet
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The protein encoded by E2F1 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.
Alias Symbols: E2F-1, RBAP1, RBBP3, RBP3
Protein Interaction Partner: RB1, SIRT1, KDM2A, LAMTOR5, EP300, KAT2B, VHL, RARA, STAT1, NCOR2, STOML1, RBL1, MAGEA11, SKP2, UHRF2, UBC, GTF2H1, ERCC3, SPT15, TFB1, TBP, NCOA3, CEBPE, PARP1, PRMT2, RBL2, CCNE1, TFDP2, TFDP1, CDKN2A, CEBPD, CDK2, CDK1, NEDD8, MCPH1, DDB2, DDB1, XIAP,
Protein Size: 437 - Poids moléculaire
- 47 kDa
- ID gène
- 1869
- NCBI Accession
- NM_005225, NP_005216
- UniProt
- Q01094
- Pathways
- Signalisation p53, Cycle Cellulaire, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagy
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