POU4F3 anticorps (Middle Region)
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- Antigène Voir toutes POU4F3 Anticorps
- POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Poisson zèbre (Danio rerio), Cobaye, Cheval, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp POU4F3 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- ALANLKIPGV GSLSQSTICR FESLTLSHNN MIALKPVLQA WLEEAEAAYR
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against POU4F3. It was validated on Western Blot and immunohistochemistry.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human POU4F3
- Top Product
- Discover our top product POU4F3 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 338 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))
- Autre désignation
- POU4F3 (POU4F3 Produits)
- Synonymes
- anticorps POU4F3, anticorps BRN-3, anticorps BRN3, anticorps BRN3C, anticorps DFNA15, anticorps BRN-3.1, anticorps brn-3c, anticorps brn3.1, anticorps brn3c, anticorps Brn3.1, anticorps Brn3c, anticorps ddl, anticorps dreidel, anticorps POU class 4 homeobox 3, anticorps POU domain, class 4, transcription factor 3, anticorps POU4F3, anticorps Pou4f3, anticorps pou4f3
- Sujet
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POU4F3 is capable of activating both BDNF and NT-3 promoters in inner ear sensory epithelial cell lines. Mutant POU4F3 loses most of its transcriptional activity and most of its ability to bind to DNA. The mutation causes autosomal-dominant nonsyndromic hearing loss and eventually leads to hair cell morbidity in affected family members.
Alias Symbols: BRN3C, DFNA15
Protein Size: 338 - Poids moléculaire
- 37 kDa
- ID gène
- 5459
- NCBI Accession
- NM_002700, NP_002691
- UniProt
- Q15319
- Pathways
- Sensory Perception of Sound
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