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POU4F3 anticorps (Middle Region)

POU4F3 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Poisson zèbre (Danio rerio), Cobaye, Cheval, Lapin WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2777732
  • Antigène Voir toutes POU4F3 Anticorps
    POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))
    Épitope
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 28
    • 11
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Boeuf (Vache), Poisson zèbre (Danio rerio), Cobaye, Cheval, Lapin
    Hôte
    • 21
    • 6
    • 1
    Lapin
    Clonalité
    • 25
    • 3
    Polyclonal
    Conjugué
    • 21
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp POU4F3 est non-conjugé
    Application
    • 19
    • 11
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    ALANLKIPGV GSLSQSTICR FESLTLSHNN MIALKPVLQA WLEEAEAAYR
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against POU4F3. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human POU4F3
    Top Product
    Discover our top product POU4F3 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 338 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))
    Autre désignation
    POU4F3 (POU4F3 Produits)
    Synonymes
    anticorps POU4F3, anticorps BRN-3, anticorps BRN3, anticorps BRN3C, anticorps DFNA15, anticorps BRN-3.1, anticorps brn-3c, anticorps brn3.1, anticorps brn3c, anticorps Brn3.1, anticorps Brn3c, anticorps ddl, anticorps dreidel, anticorps POU class 4 homeobox 3, anticorps POU domain, class 4, transcription factor 3, anticorps POU4F3, anticorps Pou4f3, anticorps pou4f3
    Sujet
    POU4F3 is capable of activating both BDNF and NT-3 promoters in inner ear sensory epithelial cell lines. Mutant POU4F3 loses most of its transcriptional activity and most of its ability to bind to DNA. The mutation causes autosomal-dominant nonsyndromic hearing loss and eventually leads to hair cell morbidity in affected family members.
    Alias Symbols: BRN3C, DFNA15
    Protein Size: 338
    Poids moléculaire
    37 kDa
    ID gène
    5459
    NCBI Accession
    NM_002700, NP_002691
    UniProt
    Q15319
    Pathways
    Sensory Perception of Sound
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