KCNA5 anticorps (N-Term)

N° du produit ABIN2778214

Détail du produit anti-KCNA5 anticorps

Antigène: KCNA5 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5))

Épitope: N-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNA5 est non-conjugé

Application: Western Blotting (WB)

Séquence: DPGVRPLPPL PEELPRPRRP PPEDEEEEGD PGLGTVEDQA LGTASLHHQR

Homologie: Human: 100%, Mouse: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against KCNA5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human KCNA5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 613 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KCNA5

Antigène: KCNA5 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5))

Autre désignation: KCNA5 (KCNA5 Produits)

Synonymes: anticorps KCNA5, anticorps kcna5, anticorps ATFB7, anticorps HCK1, anticorps HK2, anticorps HPCN1, anticorps KV1.5, anticorps PCN1, anticorps Kv1.5, anticorps Kv1, anticorps potassium voltage-gated channel subfamily A member 5, anticorps potassium channel, voltage gated shaker related subfamily A, member 5, anticorps potassium voltage-gated channel, shaker-related subfamily, member 5, anticorps KCNA5, anticorps kcna5, anticorps Kcna5

Sujet: Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). KCNA5 encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion.
Alias Symbols: ATFB7, HCK1, HK2, HPCN1, KV1.5, MGC117058, MGC117059, PCN1
Protein Interaction Partner: SIRT1, KCNAB2, ERBB2IP, SNTA1, HSP90AA1, TNK2, Rab11a, DCTN2, GNB2L1, KCNAB1, TFRC, SRC, PRKCQ, PRKCB, KCNA5, KCNA4, KCNA3, KCNA2, FYN, FHL1, DYNC1I1, CAV1, ACTN2, UBE2I, SUMO3, RAB5A, RAB4A, DLG4, DLG1, PTPRE,
Protein Size: 613

Poids moléculaire: 67 kDa

ID gène: 3741

NCBI Accession: NM_002234, NP_002225

UniProt: P22460