NFATC1 anticorps (C-Term)
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- Antigène Voir toutes NFATC1 Anticorps
- NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Cobaye, Chien, Boeuf (Vache), Cheval, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NFATC1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- LLPEVHEDGS PNLAPIPVTV KREPEELDQL YLDDVNEIIR NDLSSTSTHS
- Homologie
- Cow: 79%, Dog: 93%, Guinea Pig: 91%, Horse: 91%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against NFATC1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human NFATC1
- Top Product
- Discover our top product NFATC1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 930 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
- Autre désignation
- NFATC1 (NFATC1 Produits)
- Synonymes
- anticorps nf-atc, anticorps nfat2, anticorps nfatc, anticorps si:ch211-198c22.2, anticorps NFATC1, anticorps 2210017P03Rik, anticorps AI449492, anticorps AV076380, anticorps NF-ATc, anticorps NFAT2, anticorps NFATc, anticorps Nfatcb, anticorps NF-ATC, anticorps NF-ATc1, anticorps NFAT, anticorps NFATmac, anticorps nuclear factor of activated T-cells 1, anticorps nuclear factor of activated T-cells 1 L homeolog, anticorps nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1, anticorps nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1, anticorps NFATC1, anticorps nfatc1.L, anticorps nfatc1, anticorps Nfatc1
- Sujet
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NFATC1 is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
Alias Symbols: MGC138448, NF-ATC, NFAT2, NFATc
Protein Interaction Partner: YWHAQ, OGT, PML, GZF1, FOXP3, HDAC4, PIAS1, SUMO1, UBE2I, RPS6KB1, RPS6KA3, HDAC2, HDAC1, HNRNPA1, TUBA1A, KPNB1, HDAC5, KAT2B, EP300, PARP1, HDAC3, PPP3R1, MAPK14, GNB2L1, PRKCA, SPI1, PIM1, EGR2, EGR1,
Protein Size: 930 - Poids moléculaire
- 100 kDa
- ID gène
- 4772
- NCBI Accession
- NM_172387, NP_765975
- UniProt
- B5B2M5
- Pathways
- Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway
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