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AARS anticorps (N-Term)

AARS Reactivité: Humain, Rat, Souris, Cobaye, Cheval, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio), Chien WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2778779
  • Antigène Voir toutes AARS Anticorps
    AARS (Alanyl tRNA Synthetase (AARS))
    Épitope
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 32
    • 9
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris, Cobaye, Cheval, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio), Chien
    Hôte
    • 30
    • 1
    • 1
    Lapin
    Clonalité
    • 32
    Polyclonal
    Conjugué
    • 22
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp AARS est non-conjugé
    Application
    • 18
    • 10
    • 9
    • 5
    • 4
    • 4
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    DSTLTASEIR QRFIDFFKRN EHTYVHSSAT IPLDDPTLLF ANAGMNQFKP
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
    Attributs du produit
    This is a rabbit polyclonal antibody against AARS. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human AARS
    Top Product
    Discover our top product AARS Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 968 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    AARS (Alanyl tRNA Synthetase (AARS))
    Autre désignation
    AARS (AARS Produits)
    Synonymes
    anticorps im:7146712, anticorps si:ch211-223o1.6, anticorps wu:fc48h07, anticorps zgc:113920, anticorps CMT2N, anticorps AI316495, anticorps C76919, anticorps sti, anticorps alanyl-tRNA synthetase, anticorps alanyl-tRNA synthetase L homeolog, anticorps aars, anticorps aars.L, anticorps AARS, anticorps Aars, anticorps LOC693023
    Sujet
    The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41 % identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41 % identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.
    Alias Symbols: CMT2N
    Protein Interaction Partner: ISG15, UBC, SUMO2, SUMO1, NEDD8, TPD52, STAT5B, SRP9, PPP2R5E, METTL1, HSF1, CALU, DPP9, NIF3L1, ANKMY2, DPP8, IPO11, EEF2K, CACYBP, ARPC1B, SAE1, TOM1L1, EIF4A3, WARS, TPD52L2, UBD, VCAM1, ITGA4, HSP90AB1, HSP90AA1, FN1, NSUN2, LARS, FARSB, UBA1, QARS, N
    Protein Size: 968
    Poids moléculaire
    107 kDa
    ID gène
    16
    NCBI Accession
    NM_001605, NP_001596
    UniProt
    P49588
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