PSMA1 anticorps (C-Term)

N° du produit ABIN2778810

Détail du produit anti-PSMA1 anticorps

Antigène: PSMA1 (Proteasome Subunit alpha Type 1 (PSMA1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Cobaye, Cheval, Lapin, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: TYLERHMSEF MECNLNELVK HGLRALRETL PAEQDLTTKN VSIGIVGKDL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PSMA1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human PSMA1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 263 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PSMA1 (ABIN2778810)

Cron, Zhu, Kushwaha, Hsieh, Merzon, Rameseder, Chen, DAndrea, Kozono: "Proteasome inhibitors block DNA repair and radiosensitize non-small cell lung cancer." dans: PLoS ONE, Vol. 8, Issue 9, pp. e73710, (2013) (PubMed).

Détails sur PSMA1

Antigène: PSMA1 (Proteasome Subunit alpha Type 1 (PSMA1))

Autre désignation: PSMA1 (PSMA1 Produits)

Synonymes: anticorps PSMA1, anticorps pros30, anticorps DDBDRAFT_0204226, anticorps DDBDRAFT_0214956, anticorps DDB_0204226, anticorps DDB_0214956, anticorps C2, anticorps HC2, anticorps Pros-30, anticorps alpha-type, anticorps NU, anticorps PROS30, anticorps CC2, anticorps zgc:92726, anticorps 143314_at, anticorps Alpha-6, anticorps CG4904, anticorps Dmel\CG4904, anticorps PROS-35, anticorps PROS-Dm35, anticorps Pros-35, anticorps Pros-Dm35, anticorps Prosalpha6, anticorps alpha6, anticorps alpha_dm, anticorps anon-SAGE:Wang-116, anticorps pros 35, anticorps pros35, anticorps proteasome subunit alpha 1, anticorps proteasome subunit alpha type 1, anticorps 20S proteasome subunit C2, anticorps proteasome (prosome, macropain) subunit, alpha type 1, anticorps proteasome subunit alpha 1 L homeolog, anticorps Proteasome alpha6 subunit, anticorps PSMA1, anticorps psma1, anticorps CNB05540, anticorps psmA1, anticorps Psma1, anticorps psma1.L, anticorps Prosalpha6

Sujet: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA1 is a member of the peptidase T1A family which is a 20S core alpha subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.
Alias Symbols: HC2, MGC14542, MGC14575, MGC14751, MGC1667, MGC21459, MGC22853, MGC23915, NU, PROS30
Protein Interaction Partner: PRDM14, CEP70, CCDC102B, GNPTAB, CEP72, KCTD9, ROPN1, ABI3, SH3GLB1, APIP, LDOC1, MTUS2, MAPRE3, MAPRE1, IKZF3, MID2, EHMT2, PNMA2, IKZF1, TRIM10, HUWE1, HOMER3, PNMA1, KRT38, BLZF1, MAD1L1, MKRN3, REL, PSMA3, MLH1, KRT31, KRT15, KRTAP5-9, GOLGA2, CDA, CC
Protein Size: 263

Poids moléculaire: 29 kDa

ID gène: 5682

NCBI Accession: NM_002786, NP_002777

UniProt: P25786

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA