OAS2 anticorps (Middle Region)

N° du produit ABIN2779107

Détail du produit anti-OAS2 anticorps

Antigène: OAS2 (2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))

Épitope: Middle Region

Reactivité: Humain, Porc, Lapin, Chien, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OAS2 est non-conjugé

Application: Western Blotting (WB)

Séquence: AKGTALKTGS DADLVVFHNS LKSYTSQKNE RHKIVKEIHE QLKAFWREKE

Homologie: Cow: 92%, Dog: 92%, Human: 100%, Pig: 100%, Rabbit: 85%

Attributs du produit: This is a rabbit polyclonal antibody against OAS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human OAS2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 719 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur OAS2

Antigène: OAS2 (2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))

Autre désignation: OAS2 (OAS2 Produits)

Synonymes: anticorps Oasl11, anticorps 2'-5'-oligoadenylate synthetase 2, anticorps 2'-5' oligoadenylate synthetase 2, anticorps 2'-5'-oligoadenylate synthetase 2, 69/71kDa, anticorps OAS2, anticorps Oas2

Sujet: OAS2 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. It is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication.This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: MGC78578
Protein Interaction Partner: UBC, CLK3, APP,
Protein Size: 719

Poids moléculaire: 82 kDa

ID gène: 4939

NCBI Accession: NM_016817, NP_058197

UniProt: P29728

Pathways: Hepatitis C