CrkL anticorps (Middle Region)

N° du produit ABIN2779341

Détail du produit anti-CrkL anticorps

Antigène: CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CrkL est non-conjugé

Application: Western Blotting (WB)

Séquence: RSSPHGKHGN RNSNSYGIPE PAHAYAQPQT TTPLPAVSGS PGAAITPLPS

Attributs du produit: This is a rabbit polyclonal antibody against CRKL. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human CRKL

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 303 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CrkL

Antigène: CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))

Autre désignation: CRKL (CRKL Produits)

Sujet: CRKL has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase and plays a role in fibroblast transformation by BCR-ABL. In addition, CRKL has oncogenic potential.
Alias Symbols: -
Protein Interaction Partner: HUWE1, UBC, BAG3, PIK3R2, DOK1, CBL, LMNA, SHANK3, GAREM, BIK, AOX1, WAC, POLR1D, TENC1, KHDRBS1, PPFIBP2, ARHGEF5, YY1, RPL31, ERBB3, ERBB2, PHC2, BCAR1, RAPGEF1, EPS15, EGFR, ABL1, STAT5A, PIK3R1, EPOR, ELAVL1, MSL1, PLEKHA1, LTBP4, PLSCR1, NOTCH2, LAMA
Protein Size: 303

Poids moléculaire: 34 kDa

ID gène: 1399

NCBI Accession: NM_005207, NP_005198

UniProt: P46109

Pathways: Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor