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Src anticorps (N-Term)

Src Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2779668
  • Antigène Voir toutes Src Anticorps
    Src (Proto-oncogene tyrosine-protein kinase Src (Src))
    Épitope
    • 28
    • 25
    • 25
    • 21
    • 21
    • 19
    • 15
    • 14
    • 11
    • 8
    • 8
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 234
    • 147
    • 124
    • 11
    • 9
    • 8
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye
    Hôte
    • 244
    • 22
    • 1
    Lapin
    Clonalité
    • 222
    • 45
    Polyclonal
    Conjugué
    • 124
    • 22
    • 19
    • 17
    • 14
    • 12
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    Cet anticorp Src est non-conjugé
    Application
    • 198
    • 139
    • 68
    • 55
    • 53
    • 35
    • 30
    • 30
    • 23
    • 12
    • 9
    • 7
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB)
    Séquence
    MGSNKSKPKD ASQRRRSLEP AENVHGAGGG AFPASQTPSK PASADGHRGP
    Homologie
    Cow: 85%, Dog: 92%, Guinea Pig: 92%, Human: 100%, Mouse: 100%, Rabbit: 77%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against SRC. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human SRC
    Top Product
    Discover our top product Src Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 536 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    Src (Proto-oncogene tyrosine-protein kinase Src (Src))
    Autre désignation
    SRC (Src Produits)
    Synonymes
    anticorps AW259666, anticorps pp60c-src, anticorps C-src1, anticorps CG7524, anticorps D-Src64B, anticorps D-src, anticorps DSRC64, anticorps DSrc, anticorps DSrc64, anticorps DSrc64B, anticorps Dm SRC1, anticorps DmHD-358, anticorps Dmel\CG7524, anticorps Dsrc, anticorps Dsrc64, anticorps Dsrc64B, anticorps HD-358, anticorps MRE5, anticorps SRC 64B, anticorps Src, anticorps Src1, anticorps Src64, anticorps c-src, anticorps dSrc, anticorps dsrc, anticorps src, anticorps src1, anticorps src64, anticorps src64B, anticorps src64b, anticorps ASV, anticorps SRC1, anticorps c-SRC, anticorps p60-Src, anticorps c-Src, anticorps PP60C-SCR, anticorps SDR, anticorps SRC proto-oncogene, non-receptor tyrosine kinase, anticorps uncharacterized LOC5574802, anticorps proto-oncogene tyrosine-protein kinase src, anticorps Rous sarcoma oncogene, anticorps Src oncogene at 64B, anticorps SRC, anticorps LOC5574802, anticorps CpipJ_CPIJ010659, anticorps Src, anticorps Src64B
    Classe de substances
    Viral Protein
    Sujet
    This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. SRC protein is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
    Alias Symbols: ASV, SRC1, c-SRC, p60-Src
    Protein Interaction Partner: PSMB9, POLR2L, POLR2K, POLR2J, POLR2I, POLR2H, POLR2G, POLR2F, POLR2E, POLR2D, POLR2C, POLR2B, POLR2A, NEDD4, MAPT, ESR1, CA3, ARRB2, UBC, SRC, SPRR2A, IKBKG, CBLC, ZNF658B, TLR4, RGS16, PTGER4, EGFR, ARRB1, TNFRSF1A, KHDRBS1, SYK, CD44, ENO1, ANXA7, PIK3
    Protein Size: 536
    Poids moléculaire
    60 kDa
    ID gène
    6714
    NCBI Accession
    NM_198291, NP_938033
    UniProt
    P12931
    Pathways
    Signalistation JAK/STAT, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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