TFAM anticorps (Middle Region)

N° du produit ABIN2779902

Détail du produit anti-TFAM anticorps

Antigène: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Épitope: Middle Region

Reactivité: Souris, Rat, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFAM est non-conjugé

Application: Western Blotting (WB)

Séquence: SESFQEAKDD SAQGKLKLVN EAWKNLSPEE KQAYIQLAKD DRIRYDNEMK

Homologie: Mouse: 100%, Rabbit: 77%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against TFAM. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of mouse TFAM

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 243 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TFAM

Antigène: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Autre désignation: TFAM (TFAM Produits)

Synonymes: anticorps tcf6, anticorps mttf1, anticorps mttfa, anticorps tcf6l1, anticorps tcf6l2, anticorps tcf6l3, anticorps mttfa-A, anticorps xl-mtTFA, anticorps MGC153358, anticorps zgc:153358, anticorps MTTF1, anticorps MTTFA, anticorps TCF6, anticorps TCF6L1, anticorps TCF6L2, anticorps TCF6L3, anticorps AI661103, anticorps Hmgts, anticorps mtTFA, anticorps tsHMG, anticorps Mttfa, anticorps transcription factor A, mitochondrial, anticorps transcription factor A, mitochondrial L homeolog, anticorps TFAM, anticorps tfam.L, anticorps tfam, anticorps Tfam

Sujet: TFAM a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this protein is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns Sayre syndrome was produced when expression of the gene was eliminated by targeted disruption in heart and muscle cells.
Alias Symbols: Hmgts, mtTFA, tsHMG, AI661103
Protein Interaction Partner: C1QBP, SNCA,
Protein Size: 243

Poids moléculaire: 27 kDa

ID gène: 21780

NCBI Accession: NM_009360, NP_033386

UniProt: P40630

Pathways: Chromatin Binding