RORC anticorps (N-Term)

N° du produit ABIN2779965

Détail du produit anti-RORC anticorps

Antigène: RORC (RAR-Related Orphan Receptor C (RORC))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RORC est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: VKFGRMSKKQ RDSLHAEVQK QLQQQQQQEQ VAKTPPAGSR GADTLTYTLG

Homologie: Dog: 85%, Guinea Pig: 79%, Human: 79%, Mouse: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against Rorc. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide corresponding to a region of Mouse

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 516 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RORC

Antigène: RORC (RAR-Related Orphan Receptor C (RORC))

Autre désignation: Rorc (RORC Produits)

Synonymes: anticorps NR1F3, anticorps RORG, anticorps RZR-GAMMA, anticorps RZRG, anticorps TOR, anticorps Nr1f3, anticorps RORgamma, anticorps Thor, anticorps RAR related orphan receptor C, anticorps RAR-related orphan receptor C, anticorps RAR-related orphan receptor gamma, anticorps RORC, anticorps Rorc

Sujet: Rorc is an orphan nuclear receptor. Isoform 2 negatively regulates expression of TNFSF6/FASL and IL2 production in T-cells. It also binds to the TEA promoter and may participate in the regulation of DNA accessibility in the TCR-Jalpha locus.
Alias Symbols: Nr1f3, RORgamma, TOR, Thor
Protein Interaction Partner: Cul3, Chd4, Ewsr1,
Protein Size: 516

Poids moléculaire: 58 kDa

ID gène: 19885

NCBI Accession: NM_011281, NP_035411

UniProt: P51450

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway