PTGES2 anticorps (Middle Region)

N° du produit ABIN2780102

Détail du produit anti-PTGES2 anticorps

Antigène: PTGES2 (Prostaglandin E Synthase 2 (PTGES2))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTGES2 est non-conjugé

Application: Western Blotting (WB)

Séquence: GAAAMYLISK RLKSRHHLQD DVRVDLYEAA NKWVTAVGKD RPFMGGQKPN

Homologie: Cow: 92%, Dog: 86%, Guinea Pig: 93%, Horse: 100%, Human: 79%, Mouse: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Ptges2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Mouse Ptges2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PTGES2

Antigène: PTGES2 (Prostaglandin E Synthase 2 (PTGES2))

Autre désignation: Ptges2 (PTGES2 Produits)

Synonymes: anticorps C9orf15, anticorps GBF-1, anticorps GBF1, anticorps PGES2, anticorps mPGES-2, anticorps Pges, anticorps 2410099E23Rik, anticorps D2Ertd369e, anticorps mPGES, anticorps mPGES-1, anticorps PTGES2, anticorps ptges2, anticorps zgc:56527, anticorps gbf1, anticorps pges2, anticorps 0610038H10Rik, anticorps C79137, anticorps Gbf1, anticorps Mpges2, anticorps Pges2, anticorps MPGES-2, anticorps prostaglandin E synthase 2, anticorps prostaglandin E synthase, anticorps prostaglandin E synthase 2-like, anticorps PTGES2, anticorps Ptges, anticorps Ptges2, anticorps ptgesl, anticorps CpipJ_CPIJ003988, anticorps CpipJ_CPIJ018524, anticorps ptges2

Sujet: The protein encoded by this gene is a Golgi membrane-associated prostaglandin E synthase candidate, which is capable of catalyzing the conversion of prostaglandin H2 to prostaglandin E2 in vitro. However, a study using mice deficient of this gene suggests that this enzyme does not contribute to prostaglandin E2 biosynthesis in vivo. This protein is synthesized as a Golgi membrane-bound protein, but its N-terminal hydrophobic region is cleaved off during protein maturation to produce the predominant soluble truncated form that still retains the enzyme activity. This soluble protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE), possibly via an interaction with CAAAT/enhancer-binding protein-beta.
Alias Symbols: 0610038H10Rik, C79137, Gbf1, Mpges2, Pges2
Protein Size: 384

Poids moléculaire: 43 kDa

ID gène: 96979

NCBI Accession: NM_133783, NP_598544

UniProt: Q8BWM0

Pathways: Interferon-gamma Pathway, Cell RedoxHomeostasis, SARS-CoV-2 Protein Interactome