MAFA anticorps (Middle Region)

N° du produit ABIN2780174

Détail du produit anti-MAFA anticorps

Antigène: MAFA (Transcription Factor MafA (MAFA))

Épitope: Middle Region

Reactivité: Souris, Rat, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAFA est non-conjugé

Application: Western Blotting (WB)

Séquence: GGGSAAQAGG APGPPSGGPG TVGGASGKAV LEDLYWMSGY QHHLNPEALN

Homologie: Cow: 79%, Mouse: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Mafa. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide corresponding to a region of Mouse

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 359 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MAFA

Antigène: MAFA (Transcription Factor MafA (MAFA))

Autre désignation: Mafa (MAFA Produits)

Synonymes: anticorps RIPE3b1, anticorps hMafA, anticorps RGD1562627, anticorps 2F1-Ag, anticorps MAFA, anticorps MAFA-L, anticorps SMaf1, anticorps mafl, anticorps L-MAF, anticorps MAFL, anticorps Maf, anticorps v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian), anticorps MAF bZIP transcription factor A, anticorps killer cell lectin-like receptor subfamily G, member 1, anticorps v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A, anticorps v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa, anticorps monocyte to macrophage differentiation-associated, anticorps Mafa, anticorps MAFA, anticorps Klrg1, anticorps mafa, anticorps mafaa, anticorps Mmd

Sujet: Mafa acts as a transcriptional factor. Mafa specifically binds the insulin enhancer element RIPE3b. Mafa cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. Mafa regulates the insulin gene transcription. Mafa is involved either as an oncogene or as a tumor suppressor, depending on the cell context.
Alias Symbols: RIPE3b1
Protein Interaction Partner: Psme3,
Protein Size: 359

Poids moléculaire: 37 kDa

ID gène: 378435

NCBI Accession: NM_194350, NP_919331

UniProt: Q8CF90

Pathways: Hormone Transport