EZH2 anticorps (N-Term)

N° du produit ABIN2780595

Détail du produit anti-EZH2 anticorps

Antigène: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Lapin, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EZH2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: KGPVCWRKRV KSEYMRLRQL KRFRRADEVK SMFSSNRQKI LERTEILNQE

Specificité: From peptide immunogen, will recognize all 5 isoforms.

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against EZH2. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human EZH2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 751 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur EZH2

Antigène: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Autre désignation: EZH2 (EZH2 Produits)

Synonymes: anticorps ENX-1, anticorps ENX1, anticorps EZH1, anticorps EZH2b, anticorps KMT6, anticorps KMT6A, anticorps WVS, anticorps WVS2, anticorps eya2, anticorps im:7149338, anticorps zgc:136376, anticorps zgc:152758, anticorps EZH2, anticorps enx-1, anticorps enx1, anticorps ezh1, anticorps kmt6, anticorps xez, anticorps Enx-1, anticorps Enx1h, anticorps mKIAA4065, anticorps ezh2, anticorps olezh2, anticorps enhancer of zeste 2 polycomb repressive complex 2 subunit, anticorps enhancer of zeste 2 polycomb repressive complex 2 subunit L homeolog, anticorps enhancer of zeste 2 polycomb repressive complex 2 subunit S homeolog, anticorps EZH2, anticorps ezh2, anticorps Ezh2, anticorps ezh2.L, anticorps ezh2.S

Sujet: EZH2 is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems.
Alias Symbols: ENX1, EZH1, KMT6, WVS2, ENX-1, KMT6A
Protein Interaction Partner: FBXW11, CEP63, HOTAIR, EED, BRCA1, SUZ12, SNAI1, SRSF1, SDCBP, UPF1, RBBP7, RBBP4, RAP1GAP, PLEC, PKM, POTEE, DHX36, AEBP2, HIST4H4, KLC4, SERPINB12, PHF5A, FIP1L1, FBXL18, CPSF7, DDX3X, DBN1, SLC25A10, COPB1, CALML3, ATP5C1, ATP5B, ATP2A2, ARG1, AR, ANXA
Protein Size: 751

Poids moléculaire: 85 kDa

ID gène: 2146

NCBI Accession: NM_001203247, NP_004447

UniProt: Q15910

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation