NR1H3 anticorps (C-Term)
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- Antigène Voir toutes NR1H3 Anticorps
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Chévre, Cheval, Lapin, Cobaye, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NR1H3 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- IHHPHDRLMF PRMLMKLVSL RTLSSVHSEQ VFALRLQDKK LPPLLSEIWD
- Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against NR1H3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human NR1H3
- Top Product
- Discover our top product NR1H3 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 447 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Phosphorylation of liver X receptor alpha selectively regulates target gene expression in macrophages." dans: Molecular and cellular biology, Vol. 28, Issue 8, pp. 2626-36, (2008) (PubMed).
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Phosphorylation of liver X receptor alpha selectively regulates target gene expression in macrophages." dans: Molecular and cellular biology, Vol. 28, Issue 8, pp. 2626-36, (2008) (PubMed).
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- Antigène
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
- Autre désignation
- NR1H3 (NR1H3 Produits)
- Synonymes
- anticorps NR1H3, anticorps LXR-a, anticorps LXRA, anticorps RLD-1, anticorps AU018371, anticorps LXR, anticorps RLD1, anticorps Unr1, anticorps LXRalpha, anticorps LXR-alpha, anticorps im:7141239, anticorps wu:fd59b01, anticorps zgc:113339, anticorps zgc:158542, anticorps nuclear receptor subfamily 1 group H member 3, anticorps nuclear receptor subfamily 1, group H, member 3, anticorps NR1H3, anticorps nr1h3, anticorps Nr1h3
- Sujet
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Interaction of NR1H3 with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. NR1H3 are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. NR1H3 Plays an important role in the regulation of cholesterol homeostasis.
Alias Symbols: LXR-a, LXRA, RLD-1
Protein Interaction Partner: RXRG, RXRB, MDFI, SUV39H1, KDM1A, BARD1, MSTO1, HSP90AA1, PIAS1, APP, NR3C1, MYC, ZXDC, TMEM161A, ING3, NCOA6, NCOR1, KAT2B, EIF3I, NRIP1, NCOA3, SRC, RXRA, FOXO3, ACTN1, SS18L1, LZTR1, EDF1, RARA, NR0B2, SYT1, PPARA, SIRT1, UBC, CEP350,
Protein Size: 447 - Poids moléculaire
- 50 kDa
- ID gène
- 10062
- NCBI Accession
- NM_005693, NP_005684
- UniProt
- Q13133
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C
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