NR2E3 anticorps (N-Term)

N° du produit ABIN2780915

Détail du produit anti-NR2E3 anticorps

Antigène: NR2E3 (Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR2E3 est non-conjugé

Application: Western Blotting (WB)

Séquence: METRPTALMS STVAAAAPAA GAASRKESPG RWGLGEDPTG VSPSLQCRVC

Homologie: Cow: 86%, Human: 100%, Mouse: 93%, Pig: 79%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against NR2E3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human NR2E3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 410 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-NR2E3 (ABIN2780915)

Hayashi, Gekka, Goto-Omoto, Takeuchi, Kubo, Kitahara: "Novel NR2E3 mutations (R104Q, R334G) associated with a mild form of enhanced S-cone syndrome demonstrate compound heterozygosity." dans: Ophthalmology, Vol. 112, Issue 12, pp. 2115, (2005) (PubMed).

Détails sur NR2E3

Antigène: NR2E3 (Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3))

Autre désignation: NR2E3 (NR2E3 Produits)

Synonymes: anticorps ESCS, anticorps PNR, anticorps RNR, anticorps RP37, anticorps rd7, anticorps LOC100228348, anticorps A930035N01Rik, anticorps wu:fj55b07, anticorps zgc:103631, anticorps nuclear receptor subfamily 2 group E member 3, anticorps nuclear receptor subfamily 2, group E, member 3, anticorps NR2E3, anticorps Nr2e3, anticorps nr2e3

Sujet: NR2E3 is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. NR2E3 is a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome.This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: PNR, RNR, rd7, ESCS, RP37
Protein Interaction Partner: BCL11A, SIN3A, DHX30, TBL3, MYBBP1A, NCOR1, HDAC3, RBL1, RBBP7, RBBP4, HDAC1, CDK9, VDR, DEDD2, RBFOX2, IRF9, ZNF232, SNAPC1, PPARG, HOXC13, NR3C1, ELAVL2, POLR3D, RARA, NR1D1, CRX, RXRB, RXRA,
Protein Size: 410

Poids moléculaire: 45 kDa

ID gène: 10002

NCBI Accession: NM_014249, NP_055064

UniProt: Q9Y5X4

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway