DEAF1 anticorps (C-Term)
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- Antigène Voir toutes DEAF1 Anticorps
- DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Cobaye, Chien, Porc, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DEAF1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- TGCHKVNYCS TFCQRKDWKD HQHICGQSAA VTVQADEVHV AESVMEKVTV
- Homologie
- Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 93%, Rat: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against DEAF1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human DEAF1
- Top Product
- Discover our top product DEAF1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 565 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))
- Autre désignation
- DEAF1 (DEAF1 Produits)
- Synonymes
- anticorps AU042387, anticorps C230009B13Rik, anticorps NUDR, anticorps SPN, anticorps ZMYND5, anticorps MYND5, anticorps spn, anticorps DEAF1, anticorps nudr, anticorps zmynd5, anticorps CG8567, anticorps DEAF-1, anticorps Deaf-1, anticorps Dmel\\CG8567, anticorps deaf1, anticorps l(3)76BDv, anticorps deformed epidermal autoregulatory factor 1 (Drosophila), anticorps DEAF1, transcription factor, anticorps DEAF1 transcription factor, anticorps deformed epidermal autoregulatory factor 1 homolog, anticorps Deformed epidermal autoregulatory factor-1, anticorps Deaf1, anticorps DEAF1, anticorps LOC509260, anticorps deaf1, anticorps deaf-1
- Sujet
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DEAF1 down-regulates transcription of those genes by binding to sequence with multiple copies of TTC[CG]G present in their own promoter and that of the HNRPA2B1 gene. DEAF1 binds to the retinoic acid response element (RARE) AGGGTTCACCGAAAGTTCA. DEAF1 activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase.
Alias Symbols: SPN, NUDR, ZMYND5
Protein Interaction Partner: IRF7, IRF3, CREB1, PELI1, PELI2, HRSP12, GSK3B, GSK3A, CDKN2A, PPP1CC, PPP1CA, CDC37, AIMP2, TK1, RAD23B, PIN1, HRAS, FHL1, CDKN1A, ASCC2, INTS1, LMO4, DEAF1,
Protein Size: 565 - Poids moléculaire
- 59 kDa
- ID gène
- 10522
- NCBI Accession
- NM_021008, NP_066288
- UniProt
- O75398
- Pathways
- Tube Formation
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