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DEAF1 anticorps (C-Term)

DEAF1 Reactivité: Humain, Souris, Rat, Cobaye, Chien, Porc, Cheval WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2781133
  • Antigène Voir toutes DEAF1 Anticorps
    DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))
    Épitope
    • 15
    • 10
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 52
    • 25
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Cobaye, Chien, Porc, Cheval
    Hôte
    • 62
    • 6
    Lapin
    Clonalité
    • 63
    • 5
    Polyclonal
    Conjugué
    • 27
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DEAF1 est non-conjugé
    Application
    • 56
    • 35
    • 13
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Séquence
    TGCHKVNYCS TFCQRKDWKD HQHICGQSAA VTVQADEVHV AESVMEKVTV
    Homologie
    Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 93%, Rat: 79%
    Attributs du produit
    This is a rabbit polyclonal antibody against DEAF1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C terminal region of human DEAF1
    Top Product
    Discover our top product DEAF1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 565 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))
    Autre désignation
    DEAF1 (DEAF1 Produits)
    Synonymes
    anticorps AU042387, anticorps C230009B13Rik, anticorps NUDR, anticorps SPN, anticorps ZMYND5, anticorps MYND5, anticorps spn, anticorps DEAF1, anticorps nudr, anticorps zmynd5, anticorps CG8567, anticorps DEAF-1, anticorps Deaf-1, anticorps Dmel\\CG8567, anticorps deaf1, anticorps l(3)76BDv, anticorps deformed epidermal autoregulatory factor 1 (Drosophila), anticorps DEAF1, transcription factor, anticorps DEAF1 transcription factor, anticorps deformed epidermal autoregulatory factor 1 homolog, anticorps Deformed epidermal autoregulatory factor-1, anticorps Deaf1, anticorps DEAF1, anticorps LOC509260, anticorps deaf1, anticorps deaf-1
    Sujet
    DEAF1 down-regulates transcription of those genes by binding to sequence with multiple copies of TTC[CG]G present in their own promoter and that of the HNRPA2B1 gene. DEAF1 binds to the retinoic acid response element (RARE) AGGGTTCACCGAAAGTTCA. DEAF1 activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase.
    Alias Symbols: SPN, NUDR, ZMYND5
    Protein Interaction Partner: IRF7, IRF3, CREB1, PELI1, PELI2, HRSP12, GSK3B, GSK3A, CDKN2A, PPP1CC, PPP1CA, CDC37, AIMP2, TK1, RAD23B, PIN1, HRAS, FHL1, CDKN1A, ASCC2, INTS1, LMO4, DEAF1,
    Protein Size: 565
    Poids moléculaire
    59 kDa
    ID gène
    10522
    NCBI Accession
    NM_021008, NP_066288
    UniProt
    O75398
    Pathways
    Tube Formation
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