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ABCC5 anticorps (C-Term)

ABCC5 Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Porc, Cheval, Lapin, Cobaye WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2781499
  • Antigène Voir toutes ABCC5 Anticorps
    ABCC5 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5))
    Épitope
    • 15
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    Humain, Rat, Souris, Boeuf (Vache), Chien, Porc, Cheval, Lapin, Cobaye
    Hôte
    • 41
    • 3
    • 3
    • 1
    Lapin
    Clonalité
    • 42
    • 6
    Polyclonal
    Conjugué
    • 18
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ABCC5 est non-conjugé
    Application
    • 33
    • 19
    • 13
    • 13
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    Western Blotting (WB)
    Séquence
    EDVWSLSKHE SSDVNCRRLE RLWQEELNEV GPDAASLRRV VWIFCRTRLI
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against ABCC5. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C-terminal region of human ABCC5
    Top Product
    Discover our top product ABCC5 Anticorps primaire
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeat freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    ABCC5 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5))
    Autre désignation
    ABCC5 (ABCC5 Produits)
    Synonymes
    anticorps ABC33, anticorps EST277145, anticorps MOAT-C, anticorps MOATC, anticorps MRP5, anticorps SMRP, anticorps pABC11, anticorps 2900011L11Rik, anticorps AI132311, anticorps Abcc5a, anticorps Abcc5b, anticorps Mrp5, anticorps abc33, anticorps abcc5, anticorps moat-c, anticorps moatc, anticorps mrp5, anticorps pabc11, anticorps smrp, anticorps ATP binding cassette subfamily C member 5, anticorps ATP-binding cassette, sub-family C (CFTR/MRP), member 5, anticorps ATP binding cassette subfamily C member 5 L homeolog, anticorps ABCC5, anticorps Abcc5, anticorps abcc5.L
    Sujet
    The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing results in multiple transcript variants.
    Alias Symbols: MRP5, SMRP, ABC33, MOATC, MOAT-C, pABC11, EST277145
    Protein Size: 231
    Poids moléculaire
    25 kDa
    ID gène
    10057
    NCBI Accession
    NM_001023587, NP_001018881
    UniProt
    O15440
    Pathways
    Glycosaminoglycan Metabolic Process
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