ABCC3 anticorps (Middle Region)

N° du produit ABIN2781505

Détail du produit anti-ABCC3 anticorps

Antigène: ABCC3 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3))

Épitope: Middle Region

Reactivité: Humain, Rat, Chien, Cobaye, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCC3 est non-conjugé

Application: Western Blotting (WB)

Séquence: KVHMKGSVAY VPQQAWIQNC TLQENVLFGK ALNPKRYQQT LEACALLADL

Homologie: Dog: 77%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Pig: 86%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against ABCC3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ABCC3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1527 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ABCC3 (ABIN2781505)

Jeong, Kim, Shin, Park, Oh, Kim, Moon, Choi, Jeong, Shin, Kim: "Increased serum bile acid concentration following low-dose chronic administration of thioacetamide in rats, as evidenced by metabolomic analysis." dans: Toxicology and applied pharmacology, Vol. 288, Issue 2, pp. 213-22, (2015) (PubMed).

Détails sur ABCC3

Antigène: ABCC3 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3))

Autre désignation: ABCC3 (ABCC3 Produits)

Synonymes: anticorps ABC31, anticorps EST90757, anticorps MLP2, anticorps MOAT-D, anticorps MRP3, anticorps cMOAT2, anticorps 1700019L09Rik, anticorps Mlp2, anticorps Mrp3, anticorps ATP binding cassette subfamily C member 3, anticorps ATP-binding cassette, sub-family C (CFTR/MRP), member 3, anticorps ABCC3, anticorps Abcc3

Sujet: ABCC3 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined, however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined, however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2
Protein Interaction Partner: UBC, MLH1,
Protein Size: 1527

Poids moléculaire: 168 kDa

ID gène: 8714

NCBI Accession: NM_003786, NP_003777

UniProt: O15438