ABCA1 anticorps (Middle Region)

N° du produit ABIN2781512

Détail du produit anti-ABCA1 anticorps

Antigène: ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))

Épitope: Middle Region

Reactivité: Souris, Humain, Rat, Chien, Cobaye, Boeuf (Vache), Cheval, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCA1 est non-conjugé

Application: Western Blotting (WB)

Séquence: NRRAFGDKQS CLHPFTEDDA VDPNDSDIDP ESRETDLLSG MDGKGSYQLK

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against Abca1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide corresponding to a region of Mouse

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 2261 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ABCA1 (ABIN2781512)

Fu, Mukhamedova, Ip, DSouza, Henley, DiTommaso, Kesani, Ditiatkovski, Jones, Lane, Jennings, Smyth, Kile, Sviridov: "ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis." dans: Cell metabolism, Vol. 18, Issue 2, pp. 225-38, (2013) (PubMed).

Détails sur ABCA1

Antigène: ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))

Autre désignation: Abca1 (ABCA1 Produits)

Synonymes: anticorps ABC-1, anticorps ABC1, anticorps CERP, anticorps HDLDT1, anticorps TGD, anticorps ABCA1, anticorps Abc1, anticorps ATP-binding cassette A1, anticorps Arabidopsis thaliana ATP-binding cassette A1, anticorps AtABCA1, anticorps im:7136239, anticorps sb:cb407, anticorps wu:fa07e06, anticorps zgc:171581, anticorps ATP binding cassette subfamily A member 1, anticorps ATP-binding cassette, sub-family A (ABC1), member 1, anticorps ATP-binding cassette A1, anticorps ATP-binding cassette, sub-family A (ABC1), member 1B, anticorps ABCA1, anticorps Abca1, anticorps abca1, anticorps abca1b

Sujet: Abca1 is a cAMP-dependent and sulfonylurea-sensitive anion transporter. Abca1 is a key gatekeeper influencing intracellular cholesterol transport.
Alias Symbols: Abc1
Protein Interaction Partner: Sptlc1, Ubc,
Protein Size: 2261

Poids moléculaire: 254 kDa

ID gène: 11303

NCBI Accession: NM_013454, NP_038482

UniProt: B1AWZ8

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism