ABCA7 anticorps (Middle Region)

N° du produit ABIN2781526

Détail du produit anti-ABCA7 anticorps

Antigène: ABCA7 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCA7 est non-conjugé

Application: Western Blotting (WB)

Séquence: DTQTRHLSGG MQRKLSVAIA FVGGSRVVIM DEPTAGVDPA SRRGIWELLL

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Abca7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide corresponding to a region of Mouse

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 2159 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ABCA7 (ABIN2781526)

Bamji-Mirza, Li, Najem, Liu, Walker, Lue, Stupak, Chan, Li, Ghani, Yang, Rogaeva, Zhang: "Genetic Variations in ABCA7 Can Increase Secreted Levels of Amyloid-β40 and Amyloid-β42 Peptides and ABCA7 Transcription in Cell Culture Models." dans: Journal of Alzheimer's disease : JAD, Vol. 53, Issue 3, pp. 875-92, (2016) (PubMed).

Détails sur ABCA7

Antigène: ABCA7 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7))

Autre désignation: Abca7 (ABCA7 Produits)

Synonymes: anticorps ABCX, anticorps Abc51, anticorps ABCA-SSN, anticorps ABCA7, anticorps ATP-binding cassette, sub-family A (ABC1), member 7, anticorps ATP binding cassette subfamily A member 7, anticorps ATP-binding cassette sub-family A member 7, anticorps Abca7, anticorps ABCA7, anticorps LOC100088822

Sujet: Abca7 plays a role in phagocytosis by macrophages of apoptotic cells.Abca7 binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. Abca7 may also mediate cholesterol efflux. Abca7 may regulate cellular ceramide homeostasis during keratinocytes differentiation.
Alias Symbols: ABCX, Abc51
Protein Size: 2159

Poids moléculaire: 237 kDa

ID gène: 27403

NCBI Accession: NM_013850, NP_038878

UniProt: Q91V24