ABCG5 anticorps (Middle Region)

N° du produit ABIN2781532

Détail du produit anti-ABCG5 anticorps

Antigène: ABCG5 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 5 (ABCG5))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCG5 est non-conjugé

Application: Western Blotting (WB)

Séquence: CGYPCPEHSN PFDFYMDLTS VDTQSKEREI ETSKRVQMIE SAYKKSAICH

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ABCG5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ABCG5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 651 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ABCG5

Antigène: ABCG5 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 5 (ABCG5))

Autre désignation: ABCG5 (ABCG5 Produits)

Synonymes: anticorps DDBDRAFT_0205617, anticorps DDBDRAFT_0215344, anticorps DDB_0205617, anticorps DDB_0215344, anticorps STSL, anticorps AW112016, anticorps cmp, anticorps sterolin-1, anticorps trac, anticorps ATP binding cassette subfamily G member 5, anticorps ATP-binding cassette, sub-family G (WHITE), member 5, anticorps ABC transporter G family protein, anticorps ABCG5, anticorps abcg5, anticorps abcG5, anticorps Abcg5

Sujet: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia.
Alias Symbols: STSL
Protein Interaction Partner: Dlg4, ABCG8,
Protein Size: 651

Poids moléculaire: 72 kDa

ID gène: 64240

NCBI Accession: NM_022436, NP_071881

UniProt: Q9H222

Pathways: Lipid Metabolism